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Radiodermatitis clinical trials

View clinical trials related to Radiodermatitis.

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NCT ID: NCT04715386 Terminated - Clinical trials for Radiation Dermatitis

Feasibility in the Prophylaxis of Radiation Dermatitis Severity

Start date: June 22, 2020
Phase:
Study type: Observational

To compare radiation dermatitis severity in irradiated skin protected by an agent verses uncovered skin based on photographs and track patient reported outcomes with use of the agent.

NCT ID: NCT04630821 Terminated - Clinical trials for Radiation Dermatitis

Utilizing Topical Sodium Hypochlorite to Ameliorate Radiation Dermatitis

Start date: February 8, 2021
Phase: N/A
Study type: Interventional

The objective of the pilot study is to determine compliance, acceptability, and feasibility of using topical sodium hypochlorite to ameliorate or reduce radiation dermatitis, and to collect preliminary data and estimates for planning a larger efficacy study. This 3-week single-arm pilot study will collect information on subject treatment compliance and feedback from subjects (and nurses/subject's treating oncologist) on the acceptability of the use of the treatment. We will also collect data on Common Terminology Criteria for Adverse Events and patient reported outcomes measured using the pain and pruritus PROMIS short-form tools and patient reported outcomes, measured using the Dermatology Life Quality Index (DLQI) tool.

NCT ID: NCT04149522 Terminated - Breast Cancer Clinical Trials

Evaluation of Mepitel Film® in Preventing Epidermitis in Patients Receiving Radiation Therapy for Breast Cancer

Start date: January 15, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this research is to evaluate the use of Mepitel Film® in preventing radiation epidermitis in patients receiving radiation treatment for breast cancer. Mepitel® Film is a thin, flexible, waterproof, and breathable film made of a soft silicone layer and polyurethane film. Mepitel ® film is not made with natural rubber latex (NRL). It is FDA approved for the management of superficial wounds, such as superficial burns. As a part of this research study, the Mepitel Film® will be placed prior to participant's first radiation treatment, and will be removed one week following the end of treatment. Throughout the study, information will be collected to analyze at the end of the research study to determine if the Mepitel Film® helps prevent skin breakdown. The subjects will be followed per standard of care and examined for skin redness, warmth or swelling as normally examined and cared for during standard radiation therapy. If radiation burns are noted, the subject will be treated normally and depending on the severity of the radiation burns, may be removed from the study treatment and treated through standard of care.

NCT ID: NCT02534129 Terminated - Radiodermatitis Clinical Trials

Topical Use of Difinsa53™ to Prevent Radiation Dermatitis

Start date: August 2015
Phase: Phase 1/Phase 2
Study type: Interventional

Phase II trial of the silibin containing cream, Difinsa53 to determine efficacy in delaying, ameliorating, or preventing radiation dermatitis in patients with breast cancer undergoing whole breast radiation.

NCT ID: NCT01701466 Terminated - Breast Cancer Clinical Trials

Neoviderm Skin Emulsion in the Prevention of Radiation Dermatitis

Start date: December 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether NeoVIDERM is effective at preventing radiation dermatitis in patients receiving external beam radiation therapy to the head and neck or breast areas.

NCT ID: NCT01597921 Terminated - Breast Cancer Clinical Trials

A DB Randomized Study of R1 and R2 WaterJel / AloeVera Jell in Prevention of Radiation Dermatitis in Breast Cancer

Start date: May 2012
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the effects of topical R1 and R2 for prophylaxis of acute radiation dermatitis in patients with breast cancer receiving radiotherapy.

NCT ID: NCT01408407 Terminated - Rectal Neoplasms Clinical Trials

Alkagin Paste in the Prevention of Radiation Dermatitis

Start date: December 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether Alkagin paste is effective at preventing radiodermatitis in patients receiving external beam radiation therapy to the perineal area.

NCT ID: NCT01367990 Terminated - Alopecia Clinical Trials

Exploratory Study of Norepinephrine to Prevent Alopecia in Head and Neck Cancer Patients Treated With Radiotherapy

Start date: July 2011
Phase: Phase 1
Study type: Interventional

The study will evaluate the safety of topical norepinephrine in head and neck cancer patients who are receiving treatment with intensity modulated radiotherapy (IMRT). The study will also provide information about whether topical norepinephrine can prevent or decrease the severity of the radiation-induced alopecia experienced by these patients.

NCT ID: NCT01263366 Terminated - Radiodermatitis Clinical Trials

Exploratory Study of Norepinephrine to Prevent Radiodermatitis in Breast Cancer Patients

Start date: January 2011
Phase: Phase 1
Study type: Interventional

This study, a nonrandomized open-label Phase I safety and exploratory study, will evaluate the safety of topical norepinephrine in post-surgical breast cancer patients who are undergoing radiation therapy. The study will also provide information about whether topical norepinephrine can prevent or decrease the severity of the radiation dermatitis experienced by these patients.