Radial Artery Clinical Trial
Official title:
A Research of Central Venous-arterial Carbon Dioxide Difference Has Guiding Significance for Severely Burn Patients in Liquid Resuscitation During Early Escharectomy
Verified date | February 2021 |
Source | Guangzhou Red Cross Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
By observing the changes of Central venous-arterial partial pressure difference of carbon dioxide [P (v-a) CO2] in liquid resuscitation during early escharectomy in patients with large-scale burns, We investigate the effect of P (v-a) CO2 on postoperative tissue perfusion and oxygenation in order to seek a more effective intergrated target plan of liquid resuscitation for burn patients.
Status | Completed |
Enrollment | 118 |
Est. completion date | December 30, 2019 |
Est. primary completion date | December 30, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 20 Years to 75 Years |
Eligibility | Inclusion Criteria: 1. ASAI-II 2. New York Heart Association classification of cardiac function I-II 3. Estimated time of operation<3h 4. The circulatory system of patients is stable after thrapy:CVP8~12 mmHg;MAP=65 mmHg;urine volume>0.5m1/kg/ h;ScvO2:=70%? Exclusion Criteria: 1. Anesthetic drug allergy or contraindication 2. Patients with cardiopulmonary system disease?cardiopulmonary function abnormality?severe inhalation injuryand severe visceral injury. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Liang Bing |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Central venous oxygen saturation | Central venous oxygen saturation in venous blood | From start anesthesia until end of anesthesia, up to a maximum of 6 hours | |
Primary | Lactic acid value | Lactic acid level in arterial blood | From start anesthesia until end of anesthesia, up to a maximum of 6 hours |
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