Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to collect data about the efficacy of utilizing distal topical heat application for dilatation of the radial artery. Transradial arterial access is widely accepted as the standard of care for cardiac catheterization procedures due to its increased patient comfort and significantly decreased risk of major vascular complications, and has been recently utilized in increasing volume by the interventional radiology community throughout the world. Due to the small size of the radial artery, catheterization may sometimes be technically difficult. Pre-procedure dilatation can make catheterization significantly easier, and studies have demonstrated the successful ability to dilate the radial artery with the use of topical nitroglycerin and lidocaine. However, the investigators hypothesize that utilizing topical heat applied distally can create a physiologic vasodilatation similar to that created with nitroglycerin and lidocaine, but at a significantly lower cost and with less risk due to no need for application of a medication which has a systemic effect with known side effects. The purpose of this study is to test the efficacy of radial artery vasodilatation with distal topical heat application.


Clinical Trial Description

The study will be designed to detect a significant increase in the radial artery diameter of healthy volunteers after the application of a warm heat pack in the palmar aspect of the hand compared to a control group without heat applied to the hand. Employees and students at OHSU will be considered for enrollment as volunteers for this minimal risk study. Informed consent will be obtained from healthy volunteers prior to enrollment. After enrollment, the healthy volunteers will be randomly assigned in a 2:1 ratio to the heat group (Group 1) or the control group (Group 2), respectively. A brief medical history will be obtained from all volunteers, including age, sex, medications, prior interventions, prior surgeries, previous medical diagnoses, allergies, and any history of prior transradial procedures. For protection of confidential health information, brief medical history will be obtained in a private area. The volunteers will then be seated and the left hand placed supinated in a comfortable position on a table. A limited ultrasound of the left radial artery will be performed using grayscale ultrasound. A skin mark will be made with a marker to identify the measurement site. All volunteers will then be given a commercially available warm heat pack and asked to hold gently in their left hand. For the control group (Group 2), the warm heat pack will not be activated. For the heat group (Group 1), the warm heat back will be activated prior to placing in the volunteer's hand. Two investigators will be present. One investigator will be measuring radial artery diameter and will not be aware if the heat pack is activated. The second investigator will be aware of the volunteer's randomly assigned group and will activate the heat pack for the volunteer if they are assigned to Group 1. Over a period of 20 minutes, repeat ultrasound of the left radial artery will be performed in 5 minute intervals. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03620383
Study type Interventional
Source Oregon Health and Science University
Contact
Status Completed
Phase Phase 1/Phase 2
Start date August 3, 2018
Completion date September 18, 2018

See also
  Status Clinical Trial Phase
Completed NCT04080700 - Korean Prospective Registry for Evaluating the Safety and Efficacy of Distal Radial Approach (KODRA)
Recruiting NCT04257747 - Qualitative and Quantitative Evaluation of Vascular Flows of Radial, Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI N/A
Completed NCT03626129 - Oximetry Guided Versus Traditional Rapid Deflation Technique for Achieving Hemostasis After Radial Procedures N/A
Completed NCT05982366 - Feasibility and Safety of the Routine Distal Transradial Approach N/A
Completed NCT05771935 - Ultrasound Guided Ulnar Versus Radial Artery in Pediatrics Undergoing Major Non Cardiac Surgery N/A
Recruiting NCT04802252 - A Diagnostic Study of Abnormal Acoustic Waves in Modern Pulse in Benign Prostatic Hyperplasia
Completed NCT04303923 - Reference Diameter and Characteristics of Distal Radial Artery by Ultrasonographic Assessement in Korean Patients
Completed NCT04001764 - Comparison of the Efficacy of Radial Artery Catheterization in Three Different Regions in Intensive Care Patients N/A
Recruiting NCT04717661 - A Diagnostic Test Study of Characteristic Sound Waves in Radial Artery of Early Pregnant Women
Completed NCT04761237 - The Value of Central Venous-arterial Carbon Dioxide Difference N/A
Completed NCT01789801 - A Randomized Study Evaluating the Role of Ultra-sound Guidance When Drawing Radial Arterial Blood Samples N/A
Recruiting NCT03405428 - Ultrasonography For Radial Artery Diameter Measurement And Its Correlation With Allen Test N/A
Completed NCT01189188 - Ultrasound Guidance for Radial Arterial Blood Sampling N/A
Recruiting NCT04861883 - A Diagnostic Test Study of Characteristic Sound Waves in the Middle and Third Trimester of Pregnancy Women
Recruiting NCT04859712 - A Diagnostic Test of Abnormal Sound Waves in Modern Pulsology of Lumbar Disc Herniation
Recruiting NCT04857736 - A Diagnostic Test Study of Characteristic Sound Waves in Radial Artery During Menstruation in Healthy Female College Students
Not yet recruiting NCT05511675 - The Effect of Cold Application on the Hemostasis, Extremity Pain And Terumo Band Usage After Transradial Angiography N/A