Clinical Trials Logo

Clinical Trial Summary

This project will provide new evidence on how to optimize medication use among older people with limited life expectancy. This will be done by testing whether a patient-centered deprescribing intervention, focused on aligning medical treatment with patients' preferences, can improve quality of life among older people with limited life expectancy.

Clinical Trial Description

In a pragmatic randomized controlled trial, this project will test whether a comprehensive and patient-centered deprescribing intervention can improve quality of life among older people with limited life expectancy. The intervention will comprise a series of consultations between the patient and general practitioner (GP) (at least three) to continuously adjust the patient's medication according to the patient's goals, needs, and preferences, thereby ensuring alignment with the patient's priorities. Thus, the purpose of this intervention is to initiate and facilitate a continued deprescribing process. The process can be summarized in eight steps: During an initial consultation (1: Consultation 0), the GP assesses patient eligibility. If the patient would like to participate, a project nurse subsequently visits the patient at home (2: Home visit) for retrieval of informed consent as well as baseline measurements. After retrieval of informed consent, patients are randomized. Patients randomized to the control group continue with usual care (consultations with their GP when needed). Patients in the intervention group receive the intervention, comprising a series of consultations between the patient and GP (at least three). During the first intervention consultation (3: Consultation 1), the patient and GP discuss how the patient feels about their medical treatment, and the GP provides the patient with written material for the patient to prepare prior to the next consultation. The patients prepare (4: Preparation) by considering and verbalizing their goals of care and treatment preferences. Simultaneously, a clinical pharmacist examines the patient's medication list and provides suggestions to the GP on which drugs can be continued and deprescribed, respectively. During the next intervention consultation (5: Consultation 2), the patient and GP discuss the patient's preferences and initiate deprescribing initiatives aligned with the patient's priorities. During a new intervention consultation (6: Consultation 3), the patient and GP follow up on the changes initiated and initiate new deprescribing initiatives if such can be identified. If needed, subsequent intervention consultations (7: Consultation X) are planned until the patient and GP consider the patient's medical treatment optimal. A project nurse visits all patients (both patients randomized to the control and intervention group, respectively) at home 3 and 6 months after first home visit to retrieve follow-up measurements (8: Follow-ups). A project nurse retrieves medication lists at 3 months, 6 months, and 12 months. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05123313
Study type Interventional
Source Odense University Hospital
Contact Carina Lundby, PhD
Phone 004523241245
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date November 2021
Completion date October 2023

See also
  Status Clinical Trial Phase
Completed NCT04281953 - Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors
Active, not recruiting NCT04746664 - Effects of Nutrition Counselling on Old Age People's Nutritional Status and Quality of Life in Bahir Dar City, North West Ethiopia N/A
Recruiting NCT04142827 - The Effect of Long Term Therapy With High Flow Humidification Compared to Usual Care in Patients With Bronchiectasis (BX) N/A
Not yet recruiting NCT04893876 - The OPERa Study: Evaluating QoL After Rectal Cancer Surgery
Recruiting NCT03813420 - Sleep Quality of Physiotherapy Students Quality of Life and Physical Activity Level
Terminated NCT03304184 - The Role of Biodentine in Class V Dental Lesions on Oral Health Related Quality of Life Phase 3
Recruiting NCT05063305 - Probiotics, Immunity, Stress, and QofL N/A
Completed NCT04059809 - Photobiomodulation for Breast Cancer Radiodermatitis Phase 2/Phase 3
Active, not recruiting NCT03525327 - University of Southern California Choreographic Institute Line Dance Study
Completed NCT03663075 - Effect of Group Education and Individual Counselling on Mental Health and Quality of Life in 45-60 Year Old Women N/A
Recruiting NCT04874584 - Culturally Tailored Nurse Coaching Study for Cancer Symptom Management N/A
Recruiting NCT04591574 - ABC - A Post Intensive Care Anaemia Management Trial N/A
Completed NCT03503838 - A Pilot Study of Online Yoga for MPN Patients N/A
Recruiting NCT03222648 - Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis N/A
Terminated NCT01228864 - Brody Belt - Alternative Method of Securing a Patient's Urinary Drainage Bag N/A
Recruiting NCT05007041 - Simultaneous RZV and aIIV4 Vaccination Phase 4
Not yet recruiting NCT04759326 - Neurorehabilitation Through Hippotherapy of a Brain Stroke N/A
Not yet recruiting NCT04497025 - Conventional Vestibular Training Versus Immersive Virtual Reality- Based Vestibular in Multiple Sclerosis N/A
Not yet recruiting NCT04386135 - DESVELA. Personal Skills as Determinants of Morbidity, Lifestyles, Quality of Life, Use of Services and Mortality.
Not yet recruiting NCT03150927 - Clinical Study of Novel Probiotic Microbial Compositeā„¢ to Treat Undernourished Young Children N/A