Relationship Between Muscle Strength and Quality of Life in ICU Survivors

Quality of Life Clinical Trial

Official title:

Relationship Between Grip and Quadriceps Strength on Quality of Life in ICU Survivors

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04503486
• Other study ID #: MQV-USI
• Status: Recruiting
• Start date: August 1, 2020
• Est. completion date: August 31, 2022

Study information

• Verified date: August 2020
• Source: University of Liege
• Contact: Anne-Françoise Rousseau, MD, PhD
• Phone: +3243667495
• Email: afrousseau[@]chuliege.be
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim is to study the impact of muscle strength measured in ICU and after ICU discharge on health-related quality of life measured after hospital discharge.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: August 31, 2022
• Est. primary completion date: August 31, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• critically ill patients with an ICU stay of at least 7 days

• collaborative

Exclusion Criteria:

• non collaborative, confusion, coma

• limb paresis or plegia

• patient refusal

Related Conditions & MeSH terms

• Critical Illness
• Grip Strength
• Muscle Strength
• Quadriceps Strength
• Quality of Life

Intervention

Diagnostic Test:
• handgrip strength
measure of handgrip strength using Jamar Dynamometer and a standardized protocol, strength expressed in kg
• quadriceps strength
maximal isometric quadriceps strength measured using a handheld dynamometer and a standardized protocol, strength expressed in Newton

Locations

Country	Name	City	State
Belgium	University Hospital of Liège	Liège

Sponsors (1)

Lead Sponsor	Collaborator
University of Liege

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	health-related quality of life	assessed using the Sarcopenia Quality of Life (SARQOL) questionnaire short form: 8 questions with qualitative responses	1 month after ICU discharge
Primary	health-related quality of life	assessed using the Sarcopenia Quality of Life (SARQOL) questionnaire short form: 8 questions with qualitative responses	3 months after ICU discharge
Primary	health-related quality of life	assessed using the Sarcopenia Quality of Life (SARQOL) questionnaire short form: 8 questions with qualitative responses	6 months after ICU discharge
Primary	health-related quality of life	assessed using the EuroQOL 5 dimensions (EQ-5D) questionnaire: a first part assess the 5 dimensions of health state (each dimension is scored from 1 to 3, 3 indicating extreme problems). A second part is visual analog scale ranging from 0 (the worst health you can imagine) to 100 (the best health you can imagine)	1 month after ICU discharge
Primary	health-related quality of life	assessed using the EuroQOL 5 dimensions (EQ-5D) questionnaire: a first part assess the 5 dimensions of health state (each dimension is scored from 1 to 3, 3 indicating extreme problems). A second part is visual analog scale ranging from 0 (the worst health you can imagine) to 100 (the best health you can imagine)	3 months after ICU discharge
Primary	health-related quality of life	assessed using the EuroQOL 5 dimensions (EQ-5D) questionnaire: a first part assess the 5 dimensions of health state (each dimension is scored from 1 to 3, 3 indicating extreme problems). A second part is visual analog scale ranging from 0 (the worst health you can imagine) to 100 (the best health you can imagine)	6 months after ICU discharge