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Pulpitis clinical trials

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NCT ID: NCT06245161 Recruiting - Clinical trials for Irreversible Pulpitis

Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of intra-osseous anesthesia using Quicksleepr5 in pain elimination during dental treatment in maxillary and mandibular primary molars, compared to conventional anesthesia.

NCT ID: NCT06240169 Active, not recruiting - Pulpitis Reversible Clinical Trials

Effect of Age on the Success of DPC Using Bio-ceramic Materials in Cariously Exposed Teeth With Reversible Pulpitis

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Study Title: - Effect of age on the success of direct pulp capping using bio-ceramic materials in cariously exposed teeth with reversible pulpitis: A Prospective clinical study. Rationale: - Preservation of pulp vitality is a critical factor in long-term tooth survival. In deep carious lesion with reversible pulpitis, vital pulp therapy procedures in the form of direct pulp capping(DPC)is more conservative treatment strategy, based on the premise that a biologically active material placed in direct contact with the pulp wound can determine the pulpal response and result in the development of a reparative hard tissue bridge to preserve pulp vitality. Patient's age may have a role in the survival rate after direct pulp capping and the role of the pulp capping material has been recognized as an important parameter for the success of treatment. Research Question : Does age has any influence on the success of DPC procedure and is there any difference between MTA and Biodentine as DPC material in cariously exposed permanent teeth with reversible pulpitis? Aim & Objectives- To evaluate the effect of age on success of Direct Pulp Capping, to evaluate the success of MTA and Biodentine as direct pulp capping agents.

NCT ID: NCT06240130 Active, not recruiting - Clinical trials for Irreversible Pulpitis

Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to to compare effect of wound lavage agents NaOCl and Chlorhexidine on the outcome of partial pulpotomy in mature permanent posterior teeth with signs and symptoms indicative of irreversible pulpitis in. The main question it aims to answer are: Does wound lavage using chlorhexidine have equal effect as NaOCl on the outcome of partial pulpotomy in mature permanent mandibular posterior teeth with clinical signs of irreversible pulpitis? Participants will of age group 18 to 45 years will be included and divided into two groups: Pulp wound lavage in partial pulpotomy using 3% NaOCl as control and using 2% Chlorhexidine as experiment

NCT ID: NCT06237985 Not yet recruiting - Clinical trials for Irreversible Pulpitis

Effect of Conservative Root Canal Instrumentation on the Release of Inflammatory Mediators in Root Canal Treatments

Start date: February 15, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the expression of inflammatory mediators in the crevicular fluid and periodontal ligament after one-visit root canal treatment of mandibular molars of patients with asymptomatic irreversible pulpitis using 3 different file systems. The main question it aims to answer is: Does conservative root canal preparation cause decreased expression of inflammatory mediators compared to conventional root canal preparation? In this context, patients will be divided into 3 groups based on the file systems as follows: ProTaper Gold, OneShape, and TruNatomy up to apical size #25. Both inflammatory mediator expression and postoperative VAS values will be compared.

NCT ID: NCT06232941 Not yet recruiting - Vital Pulp Therapy Clinical Trials

Comparative Evaluation of Three Pulpotomy Agents for Permanent Mature Molars With Irreversible Pulpitis

Start date: April 1, 2024
Phase: N/A
Study type: Interventional

Statement of the problem: Accurate pulpal diagnosis is essential for decision making between vital pulp therapy and root canal treatment. Clinical and radiographic examinations do not correctly reflect the histological state of the pulp and consequently its ability to heal. Also, despite the various advantages of using MTA as a pulp capping agent, it has several drawbacks. Aim of the study: The aim of the study is to compare two types of calcium silicate-based materials to MTA in permanent mature molars diagnosed with irreversible pulpitis regarding the following parameters; level of inflammatory biomarker level, clinical and radiographic outcomes. Materials and methods: Thirty-six patients with mature permanent molars exhibiting signs and symptoms indicative of irreversible pulpitis will be enrolled. A careful periodontal treatment and standardized operative procedure will be followed for all participants. Gingival crevicular fluid samples will be obtained before any local anesthetics' administration, followed by isolation of teeth with a dental dam and removal of caries. Pulpotomy will be performed using sterile round bur till level of orifices and then haemostasis will be achieved using sodium hypochlorite. At this point, patients will be randomly divided into three groups of 12 depending on the type of calcium silicate-based material used. Later, resin modified glass ionomer will be applied, etching, bonding and placement of composite as the permanent restoration. Follow up clinically and radiographically will be done.

NCT ID: NCT06231290 Recruiting - Clinical trials for Irreversible Pulpitis

The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth

Start date: March 20, 2024
Phase: N/A
Study type: Interventional

The goal of this interventional randomized clinical trial is to test the effect of magnification and clinical experience of the operator on the success rate of full pulpotomy in mature adult molar teeth. The main questions it aims to answer are: - Does the use of magnification raise the success rate of full pulpotomy of mature adult molars? - Does the clinical experience of the operator dentist raise the success rate of full pulpotomy of mature adult molars? Participants will be asked to do the following: - Receive the pulpotomy treatment of their target molar tooth. - Record the pain score in the pain assessment chart. - Attend the follow-up visits. They'll receive a full pulpotomy treatment of their target molar tooth. Researchers will evaluate the usage of magnification in performing the pulpotomy procedure of adult molar teeth by postgraduate or undergraduate operators in comparison to performing the same pulpotomy procedure without magnification to see if it raises the overall success rate of pulpotomy.

NCT ID: NCT06226870 Not yet recruiting - Clinical trials for Endodontically Treated Teeth

Outcome of NSRCT Versus VPT in Management of Teeth With Symptomatic Irreversible Pulpitis Associated With Apical Periodontitis

Start date: May 2024
Phase: N/A
Study type: Interventional

Pulpitis is the pulpal inflammation in response to irritants which are either microbial, chemical, or physical (mechanical and thermal) in origin. Clinically, pulpitis is termed as reversible or irreversible, whereas histologically, it is described as acute, chronic or hyperplastic . Pulpitis is considered reversible when the pulp can heal following conservative management . For such cases, a coronal pulpotomy is considered as a definitive treatment option having 78% to 90% of success rate . In irreversible pulpitis (IP), the pulp is not capable of healing, thus it is treated traditionally complete pulpectomy.

NCT ID: NCT06216951 Recruiting - Post Operative Pain Clinical Trials

Post-Operative Pain After Vital Pulpotomy in Molars With Symptomatic Pulpitis

POPAVPT
Start date: December 15, 2021
Phase:
Study type: Observational

The goal of this clinical trial is to investigate post-operative pain (PEP) in teeth with symptomatic pulpitis following Vital Pulpotomy Treatments (VPT) with Calcium Silicate Cement (CSC). The main questions it aims to answer are: - Is the post-operative pain one week after VPT significantly lower than pre-operative pain in permanent molars with symptomatic pulpitis? - How does post-operative pain in these teeth correlate with patient-related factors, such as age, gender, and painkiller intake? Participants will: - Undergo Vital Pulpotomy Treatment with Calcium Silicate Cement (MTA) - Provide pain level assessments before VPT, immediately post-treatment, and at 24, 72 hours, and 1 week after treatment. If there is a comparison group: Researchers will compare the post-operative pain levels in teeth with symptomatic pulpitis undergoing VPT to assess its effectiveness in reducing pain compared to a control group not undergoing the treatment.

NCT ID: NCT06206304 Completed - Post-operative Pain Clinical Trials

Relationship of Eye Colour With Anesthetic Success and Post-Operative Pain

Start date: June 18, 2023
Phase:
Study type: Observational

Current evidence indicates that some phenotypic characteristics, such as eye or hair color, might be associated with the experience of pain. We therefore compared the anaesthetic success rate of inferior alveolar nerve block (IANB), and post-operative pain scores between light and dark eyed in female patients experiencing symptomatic irreversible pulpitis (SIP) in a mandibular molar. 110 adult patients, experiencing moderate or severe pain with SIP, participated in this prospective study. All patients received IANB of 4% articaine with 1:100.000 epinephrine. Endodontic access cavity preparation was initiated after confirmed of IANB with numbness of the lower lip. Pain during treatment was recorded by using a Heft Parker Visual Analog Scale. Anaesthetic success was recorded as ''none'' or ''mild'' pain. Root canal treatment was performed, with standardized protocols. Post-operative pain scores were also recorded 24, 48, 72 hours and 7 days after treatment.

NCT ID: NCT06201871 Recruiting - Clinical trials for Pulpitis - Irreversible

Effect of Alcohol Consumption on the Success Rates

Start date: January 2, 2024
Phase: N/A
Study type: Interventional

This prospective, randomized, double-blind clinical trial will be carried out Conservative Dentistry, Faculty of Dentistry, Jamia Millia Islamia. Seventy adult patients (35 alcoholic and 35 non-alcoholics) with symptomatic irreversible pulpits in a mandibular first or second molar will receive an IANB with 2% lidocaine. In case of pain during treatment, the procedure will be stopped, and the patients will be asked to rate the pain on the Heft-Parker scale. The injection shall be considered as successful if the patient reports pain scores less than 55 on the HP scale.