Clinical Trials Logo

Clinical Trial Summary

to evaluate the effect of a single intraligamentary injection of piroxicam on postoperative pain associated with endodontic procedures.

Clinical Trial Description

The pain after endodontic treatment is commonly severe in the first 24 hours after treatment, then it will reduce gradually until commonly disappearing after 7-10 days in most cases. Since piroxicam has a half-life of 50 hours in the plasma, it will be effective in controlling the most intense pain which occurs after endodontic treatment It appears that optimal clinical benefits can be achieved by administering drugs such as local anesthetics and NSAIDs before the onset of postoperative pain. Administering these drugs before a surgical or an endodontic procedure may be of benefit for longer procedures or for minimizing peripheral sensitization, which is a result of the cascade of inflammatory mediators that are released by tissue injury and fuel the subsequent inflammatory process ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

NCT number NCT03006107
Study type Interventional
Source Cairo University
Contact marwa ga ahmed, student
Phone 01286171420
Email [email protected]
Status Not yet recruiting
Phase N/A
Start date December 2016
Completion date January 2018

See also
  Status Clinical Trial Phase
Recruiting NCT03956199 - Pulpotomy vs.Root Canal Treatment in Managing Irreversible Pulpitis N/A
Completed NCT03174860 - Effect of Preoperative Diclofenac Potassium on Articaine Buccal Infitration Success Phase 2/Phase 3
Not yet recruiting NCT03612323 - Comparison Between Intraligamentary Piroxicam and Articaine Early Phase 1
Not yet recruiting NCT02953912 - Assessment of Postoperative Pain Using Reciproc Versus One Shape Files in Patients With Irreversible Pulpitis N/A
Active, not recruiting NCT04308863 - Evaluation of Chitosan Scaffold and Mineral Trioxide Aggregate Pulpotomy in Mature Permanent Molars With Irreversible Pulpitis Phase 2
Recruiting NCT04719247 - Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy Medicaments in Primary Teeth N/A
Recruiting NCT03553407 - Analgesic Effect of Low Intensity Laser in Patients With Pulpitis of Mandibular Molars. N/A
Not yet recruiting NCT03916900 - Postoperative Pain and Success Rate in Pulpotomy Versus Root Canal Treatment N/A
Not yet recruiting NCT02952300 - Post Operative Pain of Root Canal Preparation With Wave One and Neolix in Acute Irreversible Pulpitis N/A
Active, not recruiting NCT04397315 - Comparative Evaluation of Partial and Complete Pulpotomy in Permanent Molars N/A
Completed NCT03116672 - The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo N/A
Completed NCT04773886 - Effectiveness of Mineral Trioxide Aggregate and Platelet Rich Fibrin Along With Biodentine. . Phase 4
Completed NCT03341260 - Effect of Preoperative Diclofenac Potassium on Postoperative Endodontic Pain Phase 2/Phase 3
Not yet recruiting NCT04669392 - The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in Pulpectomy Compared to Normal Saline in Primary Molars Early Phase 1