Pulp Necroses Clinical Trial
Official title:
Magnetic Resonance Imaging Assessment of Pulp Regeneration Following Regenerative Endodontic Procedures in Mature Teeth
Verified date | January 2019 |
Source | Alexandria University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The present study was conducted to test whether pulp-like tissue can be regenerated in mature teeth with closed apex? And whether the size of the apical diameter affects the success of REPs? And whether Magnetic resonance imaging (MRI) can be used to quantitatively assess the vitality of the regenerated pulp-like tissue.
Status | Completed |
Enrollment | 18 |
Est. completion date | December 28, 2018 |
Est. primary completion date | September 3, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 20 Years to 40 Years |
Eligibility |
Inclusion Criteria - Upper anterior mature teeth with single canals. - Necrotic teeth - Presence of periapical lesion. Exclusion Criteria: - Presence of systemic diseases. - Presence of stainless steel wires o brackets - Vital immature teeth with open apex |
Country | Name | City | State |
---|---|---|---|
Egypt | Alexandria University | Alexandria |
Lead Sponsor | Collaborator |
---|---|
Alexandria University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | MRI assessment of pulp-like tissue regeneration | Signal intensity of the regenerated pulp-like tissue was quantitatively measured in both test and control groups after 3,6 and 12 months follow up and compared to the contralateral normal teeth. | 12 months | |
Secondary | Healing of the periapical lesion | Cone beam computed tomography (CBCT) was used to assess the healing of the periapical lesion after 12 months follow up period. | 12 months | |
Secondary | Positive pulpal response | The positive response to sensibility tests using cold test and electric pulp tester was done after 3,6,9 and 12 months | 12 months |
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