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Pulmonary Nodule, Solitary clinical trials

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NCT ID: NCT05963945 Completed - Pleural Effusion Clinical Trials

Multi-Reader Retrospective Study Examining Carebot AI CXR 2.0.21-v2.01 Implementation in Everyday Radiology Clinical Practice

Start date: October 18, 2022
Phase:
Study type: Observational

The primary objective is to evaluate the performance parameters of the proposed DLAD (Carebot AI CXR) in comparison to individual radiologists.

NCT ID: NCT05350137 Completed - Lung Cancer Clinical Trials

Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy

Start date: February 11, 2022
Phase: N/A
Study type: Interventional

With the increasing acceptance of routine computed tomography (CT) screenings, early-stage lung cancer detection is becoming more frequent. For ground glass opacity predominant early-stage lung cancer, segmentectomy can get the same oncological benefits as lobectomy. In addition, lung nodules that are highly suspected to be metastases can also be performed by segmentectomy to preserve more lung function. During the surgery, the rapid and precise identification of the intersegmental plane is one of the challenges. The improved inflation-deflation method is currently the most widely used method in clinical practice. According to the dispersion coefficient of the gas, the rapid diffusion properties of carbon dioxide would be expected to speed lung collapse and so facilitate surgery. The purpose of this study was to investigate the feasibility and safety of carbon dioxide on the appearance time of satisfactory and ideal planes during segmentectomy.

NCT ID: NCT04735341 Completed - Lung Cancer Clinical Trials

Prospective Post-market Data Collection for Ion Endoluminal System to Understand CT to Body Divergence

Start date: December 9, 2020
Phase:
Study type: Observational

The goal of this study is to collect post-market data for the Ion Endoluminal System to understand CT to body divergence.

NCT ID: NCT04302350 Completed - Lung Cancer Clinical Trials

Nitrous Oxide for Identifying the Intersegmental Plane in Segmentectomy: A Randomized Controlled Trial

Start date: January 15, 2020
Phase: N/A
Study type: Interventional

Lung cancer is currently one of the most common malignant tumors in the world. In recent years, with the popularity of high-resolution CT, more and more early-stage lung cancers have been found. Anatomic pneumonectomy is gradually popular because it can completely remove lung nodules and preserve lung function to the greatest extent. During the surgery, the precise and rapid determination of intersegmental border is one of the key technologies. Improved inflation-deflation method is currently the most widely used method in clinical practice. Previous studies demonstrated that increasing the concentration of nitrous oxide in mixtures of N2O/O2 will lead to a faster rate of collapse. The rapid diffusion properties of N2O would be expected to speed lung collapse and so facilitate surgery. This study was designed to explore three types of inspired gas mixture used during two-lung anesthesia had an effect on the intersegmental border appearance time during pneumonectomy and its feasibility and safety: 75% N2O (O2: N2O = 1: 3), 50% N2O (O2: N2O = 1: 1), 100% oxygen.

NCT ID: NCT04209972 Completed - Clinical trials for Pulmonary Nodule, Solitary

The Benefit of UHR-CT: Precision of Repeated Volume Measurements of Pulmonary Nodules

Coffee Break
Start date: March 11, 2019
Phase: N/A
Study type: Interventional

To assess the variability of semi-automated volume measurements of pulmonary nodules on same-day repeated scans of equal radiation dose from two different CT scanners: One high-end CT scanner with standard spatial resolution (CT1) and one UHRCT scanner (CT2), in patients with known or suspected pulmonary metastases.

NCT ID: NCT04076696 Completed - Clinical trials for Pulmonary Nodule, Solitary

Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis

Start date: August 26, 2020
Phase: N/A
Study type: Interventional

This is a study that will evaluate the utility of a scatter reduction technique in reducing dose and increasing the sensitivity of stationary digital chest tomosynthesis (s-DCT) in the detection of lung lesions.

NCT ID: NCT04066699 Completed - Clinical trials for Pulmonary Nodule, Solitary

Percutaneous Localization: Open-label Registry of Thoracic Surgery

PLOTS
Start date: October 10, 2019
Phase:
Study type: Observational [Patient Registry]

The objectives of this study are to evaluate intraoperative percutaneous lung lesion marking assisted by electromagnetic guided percutaneous navigation and related tools.

NCT ID: NCT04056923 Completed - Lung Cancer Clinical Trials

3D Printing for Nodule Localization

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Implementation of lung cancer screening using low-dose computed tomography has increased the rate of detection of small peripheral pulmonary nodules. However, it is hard to localize these nodules by palpation because of their small volume and long distance to the nearest pleural surface. To further clarify the confounding factors, we developed our own 3D printing localization procedure. In contrast to traditional CT-G percutaneous puncture localization, our procedure was performed in the operating room without CT scan evaluation.

NCT ID: NCT03989219 Completed - Clinical trials for Pulmonary Nodule, Solitary

Methylation of cfDNA in Diagnosing and Monitoring Pulmonary Nodule

Start date: August 15, 2018
Phase:
Study type: Observational

Patients found pulmonary nodules by CT screening by will be enrolled in this study prospectively. Plasma cfDNA sequencing of these patients will be used to diagnose and monitor benign and malignant pulmonary nodules.

NCT ID: NCT03753724 Completed - Lung Cancer Clinical Trials

IDEAL: Artificial Intelligence and Big Data for Early Lung Cancer Diagnosis Study

IDEAL
Start date: August 29, 2018
Phase:
Study type: Observational

This study aims to test the use of novel CT image analysis techniques to enable a better characterisation of small pulmonary nodules. The study will incorporate solid and predominantly solid nodules of 5-15 mm scanned using a variety of scanner types, imaging protocols and patient populations. The investigators hope that the new image processing techniques will improve the accuracy of lung nodule analysis which will in turn reduce the number of unnecessary investigations for benign nodules and may increase the accuracy of the early diagnosis of lung cancer in malignant nodules. This study aims to test this novel analysis software to subsequently allow validation.