Clinical Evaluation of Primary Sampling Scatter Correction for Chest

Status Completed

Clinical Trial Summary

This is a study that will evaluate the utility of a scatter reduction technique in reducing dose and increasing the sensitivity of stationary digital chest tomosynthesis (s-DCT) in the detection of lung lesions.

Clinical Trial Description

Digital tomosynthesis is an imaging modality that produces 3D sectional information using x-ray projections acquired over a limited scanning angle. Scatter is known to be the primary source of image degradation in x-ray based imaging. The investigators have developed an approach that measures scatter through a low dose (3% of the conventional scan) scatter measurement technique. Preliminary studies have shown that scatter reduction in DCT can significantly improve quality. The approach will characterize the reader confidence in lung nodule detection in a scatter corrected chest tomosynthesis imaging approach as compared to the conventional chest tomosynthesis. Fifty (50) patients who have undergone a clinical non-contrast CT with lung nodules will be asked to have an s-DCT (scan) within 4 weeks (+/- 2 week) of their clinical CT with no intervening procedures or therapies (i.e. biopsy of lung nodules). Investigators will then perform a reader study to evaluate the radiologist reader confidence in images generated from the scatter reduction technique versus more conventional chest tomosynthesis imaging. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04076696
Study type	Interventional
Source	UNC Lineberger Comprehensive Cancer Center
Contact
Status	Completed
Phase	N/A
Start date	August 26, 2020
Completion date	August 26, 2021

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Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms