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Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction — PH-HFpEF  

Heart Failure Clinical Trial

Official title:
Phase II Clinical Investigation of Oral Nitrite in Patients With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (PH-HFpEF)

Clinical Trial Summary

The main objective of this study is to determine the clinical efficacy of oral inorganic nitrite verses placebo and the therapeutic response with regards to exercise tolerance in patients with pulmonary hypertension and heart failure with preserved ejection fraction (PH-HFpEF).

Clinical Trial Description

This is a single-center, 22-week double-blind, randomized placebo-controlled cross-over trial of oral nitrite on exercise capacity and hemodynamic measurements in subjects with PH-HFpEF. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03015402
Study type Interventional
Source University of Pittsburgh
Contact
Status Completed
Phase Phase 2
Start date October 30, 2017
Completion date January 25, 2023
View Details
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