Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath Condensate

Pulmonary Function Clinical Trial

Official title:

Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT01719393
• Other study ID #: 201207062RIC
• Status: Not yet recruiting
• Phase: N/A
• First received: October 30, 2012
• Last updated: October 31, 2012
• Start date: November 2012
• Est. completion date: December 2013

Study information

• Verified date: October 2012
• Source: National Taiwan University Hospital
• Contact: Ping-Hung Kuo
• Phone: 886-2-23123456
• Email: kph712[@]ntuh.gov.tw
• Is FDA regulated: No
• Health authority: Taiwan: National Taiwan University Hospital
• Study type: Observational

Clinical Trial Summary

Our hypothesis is that radial arterial pulse may reflect the severity and airway function in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its correlation with airy inflammation an lung funtion in asthmatics.

Description:

The microcirculation is directly involved in the cellular matabolism and homeostasis. Our hypothesis is that radial arterial pulse spectrum may reflect the airway condition in asthmatics. The aims of this study are to investigate the pulse spectrim of the radial artery in adult asthmatics, and evaluate its correlation with lung function, asthma control status,exhaled nitric oxide, and metabolites in the exhaed breath condensates.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: December 2013
• Est. primary completion date: November 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Meet the diagnostic criteria of GINA guideline asthma patients

Exclusion Criteria:

• Cancer or immune impaired patients;

• pack-year smoking> 5;

• long-term ventilator-dependent patients

• Control group: 30 age matched healthy controls

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• FeNO
• Metabolites
• Pulmonary Function
• Pulse Spectrum Analysis

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pulse spectral analysis		one year	No