Clinical Trials Logo

Clinical Trial Summary

Lung function impairment is common after abdominal surgery. Few preventive strategies exist against postoperative lung function impairment. A new potential preventive strategy against postoperative lung function impairment comes from research on critically ill patients with severe respiratory failure. In this field research has long focused on influence of breathing volume (= tidal volume) during mechanical ventilation on outcome. It has been shown, that low tidal volumes improve patients outcomes as compared to (conventional) high tidal volumes. Therefore, we propose a patient and investigator blinded randomised trial to test the hypotheses that intraoperative mechanical ventilation with low tidal volumes as compared to high tidal volumes reduces postoperative lung function impairment in high risk patients.


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Prevention


Related Conditions & MeSH terms


NCT number NCT00795964
Study type Interventional
Source Heinrich-Heine University, Duesseldorf
Contact
Status Completed
Phase N/A
Start date September 2008
Completion date September 2010

See also
  Status Clinical Trial Phase
Completed NCT03255187 - Effect of Dietary Supplemental Fish Oil in Alleviating Health Hazards Associated With Air Pollution N/A
Completed NCT02239744 - Intervention Study on the Health Impact of Air Filters in Chinese Adults N/A
Completed NCT04880486 - Weight Training With VR in Out-Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease N/A
Completed NCT03697174 - Acute Health Effects of Ozone Exposure N/A
Completed NCT02200289 - In Utero Household Air Pollution Exposure and Lung Development in Ghana N/A
Withdrawn NCT00749762 - Pulmonary Function During Prone and Supine Positioning in NICU Infants Requiring Assisted Ventilation N/A
Recruiting NCT06106646 - Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up
Completed NCT04256070 - Effect of Education and Tele-consultancy Intervention Based on Watson Human Care Theory Individuals With COPD N/A
Recruiting NCT05190497 - Effects of IMT on Pulmonary Functions IN CASES With Inhalation Injury N/A
Completed NCT02151669 - Diet Intervention Spirometry and Tobacco N/A
Not yet recruiting NCT01719393 - Pulse Spectrum Analysis in Adult Asthmatics: Correlation With Lung Function, Asthma Control Exhaled Nitric Oxide and Metabolites in Exhaled Breath Condensate N/A
Completed NCT06073275 - Effects of Beetroot Juice Intake on Performance and Physiological Parameters N/A
Completed NCT03885583 - Post-operative Pulmonary Function After Kidney Surgery Under Two Different Techniques N/A
Completed NCT04734743 - Muscle Strength, Functional Capacity, Respiratory Function and Quality Of Life In Cystic Fibrosis Patients N/A
Enrolling by invitation NCT02825654 - Service and Health Among Deployed Veterans
Recruiting NCT03203603 - VCSIP Follow-up Study
Completed NCT05023876 - The Effect of Instrument Assisted Soft Tissue Mobilization on Respiratory Functions in Chronic Obstructive Pulmonary Disease N/A
Recruiting NCT03206710 - Vitamin C Supplementation to Pregnant Smokers: Follow-up of 2 Randomized Trials Plus Changes in DNA Methylation
Completed NCT03167918 - Lung Function in Patients With Early Type 2 Diabetes Mellitus Phase 2/Phase 3
Active, not recruiting NCT01728571 - LungVITamin D and OmegA-3 Trial (lungVITAL) N/A