Clinical Trials Logo

Pulmonary Emphysema clinical trials

View clinical trials related to Pulmonary Emphysema.

Filter by:

NCT ID: NCT01602523 Active, not recruiting - Emphysema Clinical Trials

Effect of Symbicort on Sleep Quality in Patients With Emphysema

Start date: March 2011
Phase: Phase 3
Study type: Interventional

This study will look at the effects of the drug Symbicort on sleep quality. Symbicort is an inhaled medication that contains 2 drugs. One is a medication that opens up the airways (formoterol). The other is a steroid to decrease airway inflammation (budesonide). Symbicort is not an experimental medication. It is approved by the Food and Drug Administration for use in patients with emphysema. Patients with severe emphysema commonly sleep poorly. The cause of poor sleep in these patients is unknown. Symbicort may improve sleep quality by opening the airways and reducing lung inflammation. It is not known for sure if these effects actually improve sleep and quality of life. It is hoped that this study will answer this question.

NCT ID: NCT01580215 Terminated - Pulmonary Emphysema Clinical Trials

Long Term Follow up Investigation of Endobronchial Valves in Emphysema

LIVE
Start date: July 2012
Phase: N/A
Study type: Observational

This is an observational prospective single arm multicentre study to observe the effect over 5 years of Zephyr endobronchial valve therapy for emphysema.

NCT ID: NCT01520740 Terminated - Pulmonary Emphysema Clinical Trials

Collateral Ventilation Effects on Response to AeriSeal System Treatment in Upper Lobe Predominant Emphysema

CV+/-
Start date: February 2012
Phase: Phase 4
Study type: Interventional

This study will evaluate the effects of baseline collateral ventilation status on outcomes following treatment with AeriSeal System in patients with advanced upper-lobe predominant heterogenous emphysema.

NCT ID: NCT01520064 Terminated - Pulmonary Emphysema Clinical Trials

Post Market Registry Study of the AeriSeal System

Start date: February 2012
Phase: N/A
Study type: Observational [Patient Registry]

- Obtain and analyze medical record data on patients with advanced emphysema who receive treatment with the AeriSeal System to better understand safety and effectiveness in the post-market setting; - Provide participating physicians access to specified data sets for the purpose of generating scientific manuscripts about the effects of AeriSeal System treatment.

NCT ID: NCT01515709 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease

Start date: April 2011
Phase:
Study type: Observational

Patients with Chronic Obstructive Lung Disease (COPD) often develop muscle problems, particularly in their legs which makes them more limited in what they can do. The Short Physical Performance Battery (SPPB) is a simple test of standing balance, usual walking speed and ability to stand from a chair. The SPPB may be a useful measure to predict leg function. This study aims to evaluate whether the SPPB is comparable with current exercise tests used in COPD patients, and whether it is useful in predicting disability, death and health resource usage over time.

NCT ID: NCT01507415 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?

Start date: November 2011
Phase: N/A
Study type: Observational

This study aims to evaluate simple tests of physical function in hospitalised patients with chronic obstructive pulmonary disease (COPD) and to assess whether they can predict future hospital readmission. The Short Physical Performance Battery (SPPB) is a simple test of standing balance, usual walking speed (4-metre gait speed) and ability to stand from a chair, which reflects global physical functioning and frailty. We hypothesise that the SPPB or 4-metre gait speed can predict future hospital readmissions.

NCT ID: NCT01495780 Completed - COPD Clinical Trials

eRT Remote Health Monitoring

Start date: January 2012
Phase: N/A
Study type: Interventional

Remote Health Monitoring (RHM) is the assessment of one's own symptoms at home between doctor visits, using things like at-home breathing tests, electronic diaries to answer questionnaires, and other monitoring devices. The hypothesis of this study is that the health and quality of life of people with COPD who do RHM for one year will be better than people with COPD who do not do RHM. Subjects who are at least 40 years old, have been diagnosed with chronic obstructive pulmonary disease (COPD), also known as chronic bronchitis or emphysema, and are current or former smokers will be invited to participate. This study is paid for by eResearch Technology (eRT). Subjects will complete 2 visits at UCLA, separated by one year of RHM. All subjects will participate in RHM. RHM will involve daily monitoring at home using a few electronic devices: blood oxygen levels, symptoms, medication use, breathing tests, and activity monitoring. Visits will include physical exam and medical history, ECG, questionnaires, breathing tests, and exercise tests.

NCT ID: NCT01460108 Recruiting - COPD Clinical Trials

AeriSeal System in Patients With Advanced Upper Lobe Predominant Emphysema and Collateral Ventilation

CV+
Start date: April 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to characterize the safety and efficacy of the AeriSeal System in patients with advanced upper lobe predominant emphysema and significant collateral ventilation as determined by the Chartis System.

NCT ID: NCT01457833 Completed - Pulmonary Emphysema Clinical Trials

Implantation of Endobronchial Valves Versus Intrabronchial Valves in Patients With Severe Heterogeneous Emphysema

Start date: August 2011
Phase: N/A
Study type: Interventional

Patients with advanced heterogeneous emphysema experience improvement in clinical outcomes in the same way following either implantation of endobronchial valves or intrabronchial valves.

NCT ID: NCT01449292 Terminated - Pulmonary Emphysema Clinical Trials

Study of the AeriSeal System for HyPerInflation Reduction in Emphysema (ASPIRE)

ASPIRE
Start date: June 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the safety and efficacy of AeriSeal System treatment plus optimal medical therapy compared in patients with advanced upper lobe predominant (ULP) heterogeneous emphysema.