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Clinical Trial Summary

IMPAHCT: Inhaled iMatinib Pulmonary Arterial Hypertension Clinical Trial is a Phase 2b/Phase 3 study to evaluate the safety and efficacy of AV-101 (dry powder inhaled imatinib) in patients with Pulmonary Arterial Hypertension (PAH). The Phase 2b part of the study will assess three doses to establish an optimal dose for the Phase 3 part of the study. The Phase 2b primary endpoint will be the placebo corrected change in pulmonary vascular resistance (PVR). The Phase 3 primary endpoint will be the placebo corrected change in 6-minute walk distance (6MWD) after 24 weeks of treatment.

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT05036135
Study type Interventional
Source Aerovate Therapeutics
Contact Toll Free Number
Phone (888) 373-8110
Email [email protected]
Status Not yet recruiting
Phase Phase 2/Phase 3
Start date November 2021
Completion date January 2025

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