Pulmonary Arterial Hypertension Clinical Trial
Official title:
Comprehensive Characterization Of Right Ventricular Performance And Afterload In Patients With Pulmonary Arterial Hypertension Undergoing Initiation And Rapid Dose Escalation Of Treprostinil
Patients with pulmonary arterial hypertension (PAH) are at much higher risk of death if the
RV (right ventricle) is weak. The purpose of this study is to get a better understanding of
the factors that determine RV adaptation and how the RV compensates on therapy. The
investigator is also interested in how Remodulin (treprostinil) infused over a short period
(approximately 48-72 hours) affects the patient's quality of life, medical care, and
personal health behaviors.
Treprostinil, also known as Remodulin, has been approved by the US Food and Drug
Administration for use in the treatment of PAH. The investigator has been treating patients
with Remodulin by rapid infusion (over 48 hours) for over 6 years. The investigator would
like to establish this practice as safe and effective for the benefit of other centers that
treat PAH.
n/a
Observational Model: Case-Only, Time Perspective: Prospective
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