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NCT00617487 Clinical Trial

Pulmonary Arterial Hypertension in Systemic Sclerosis

Pulmonary Arterial Hypertension Clinical Trial

Official title:
Stress Echocardiography in the Early Identification of Pulmonary Arterial Hypertension in Systemic Sclerosis

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00617487
Other study ID # EchostressSSc
Secondary ID
Status Active, not recruiting
Phase N/A
First received February 6, 2008
Last updated March 6, 2018
Start date December 2007
Est. completion date January 2020

Study information
Verified date March 2018
Source IRCCS Policlinico S. Matteo
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to evaluate the role of stress echocardiography, compared to standard echocardiography in the early identification of pulmonary arterial hypertension in systemic sclerosis. To evaluate the role of BNP in this setting.To analyze data recorded with respect to the parameters commonly used for SSc evaluation (eg thorax HRCT, pulmonary function tests + DLCO, nailfold capillaroscopy, etc); these parameters are available starting for 1999.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 200
Est. completion date January 2020
Est. primary completion date March 2018
Accepts healthy volunteers No
Gender All
Age group 18 Years to 90 Years
Eligibility Inclusion Criteria:

- Patients with systemic sclerosis according to LeRoy criteria

Exclusion Criteria:

- Pregnancy

- Significant valvular disease

- Low left ventricular function upon echocardiography (ejection fraction<55%)

- History of atrial fibrillation, myocardial infarction, pulmonary thromboembolisms, neoplasia or severe hepatic disease.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Italy IRCCS Foundation Policlinico S. Matteo Pavia PV
Italy IRCCS Policlinico S. Matteo Pavia PV

Sponsors (1)
Lead Sponsor Collaborator
IRCCS Policlinico S. Matteo

Country where clinical trial is conducted

Italy, 

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