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Ptosis, Eyelid clinical trials

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NCT ID: NCT03916107 Enrolling by invitation - Ptosis, Eyelid Clinical Trials

Comparison of Different Surgical Treatments for Severe Ptosis Correction

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Main research purposes of this research is to compare the therapeutic effect and safety of the superior levator muscle shortening combined with the tarsus resection and the traditional frontal muscle flap in the correction of severe ptosis. Aside of above we also tend to explore the dose-effect relationship between the amount of levator muscle shortened/ tarsus resection and postoperative ptosis correction amount.So as to develop a more critical and specific guidelines for clinical treatment of ptosis. So during the research we will recruiting patients with severe ptosis and randomly divide them into levator muscle and tarsus group and frontal muscle flap group, and follow up those patient 6 months post operation so as to evaluate the amount of correction and the side-symptoms.

NCT ID: NCT03818204 Completed - Stroke Clinical Trials

Clinical Trial to Improve the Magnetic Levator Prosthesis

Start date: February 7, 2019
Phase: N/A
Study type: Interventional

Blepharoptosis (incomplete opening of the eyelids) occurs because of a disruption in the normal agonist-antagonist neuro-muscular complex balance. An external device could restore eyelid movement. A newer class of permanent magnets made of alloys of neodymium (Nd), iron (Fe) and boron (B) might provide the technology needed to develop a feasible external magnetic device that could restore eyelid movement.

NCT ID: NCT03392272 Not yet recruiting - Clinical trials for Surgical Procedure, Unspecified

Modified Müller's Muscle-conjunctival Resection Internal Ptosis Repair Using Fibrin Glue

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Fibrin glue is widely used in ophthalmology for homeostasis and tissue recovery. It is commonly used in ocular surface surgeries such as pterygium removal and conjunctival lesions excisions. In Müller's muscle-conjunctival resection (MMCR), sutures are used to reconnect the conjunctiva and Muller muscle, which causes discomfort and pain for the patient. The investigators' goal is to explore using fibrin glue instead of sutures in MMCR surgeries to shorten the procedure's length and alleviate patients discomfort and pain. This is especially important in the management of children suffering ptosis, where sedation and even general anaesthesia is required for sutured removal as a secondary procedure.

NCT ID: NCT01616108 Recruiting - Strabismus Clinical Trials

Bupivacaine Injection of Eye Muscles to Treat Strabismus

Start date: April 2012
Phase: Phase 2/Phase 3
Study type: Interventional

This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus. It seeks further to find out the different effects of various concentrations or formulations of bupivacaine, and whether addition of Botox to other eye muscles can add to the effect of bupivacaine and enhance the correction of strabismus.

NCT ID: NCT00753831 Completed - Ptosis, Eyelid Clinical Trials

Efficacy of Aurosling in Frontalis Sling Suspension Surgery

Start date: January 2009
Phase: Phase 4
Study type: Interventional

To Study the Efficacy of Aurosling as a suspension material in Frontalis suspension surgery in ptosis