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Ptosis, Eyelid clinical trials

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NCT ID: NCT05890027 Recruiting - Ptosis, Eyelid Clinical Trials

Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation

Start date: March 19, 2024
Phase: Phase 4
Study type: Interventional

This research study aims to compare whether Phenylephrine 2.5% ophthalmic eye drop solution can serve as a better indicator of the effect of a drooping upper eyelid (ptosis) by covering part of the upper portion of the field of vision as compared to traditional use of tape to lift up the upper eyelid in the evaluation of patients for surgical upper eyelid repair.

NCT ID: NCT05750251 Recruiting - Eyelid Diseases Clinical Trials

Effect of Upper Eyelid Surgeries on Corneal Characteristics

Start date: February 6, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this prospective observational study is to learn about the impact of conventional eyelid correction surgery on the eye's health and function in ptosis and eyelid retraction patient. The main questions it aims to answer are: • 1. Changes in corneal topography, higher-order corneal aberrations, corneal biomechanical characteristics, and corneal epithelial thickness before and after the surgery 2. Influence of corneal refraction examinations , vision change, and tear film function after the surgery Fifty participants will undergo conventional eyelid correction surgery by the same ophthalmologist (YH Wei) and non-invasive examinations before and after the surgery. The patient will be separate to 2 groups, including 30 with correction for ptosis and 20 with correction for eyelid retraction. The research will collect information of the operated eye and fellow eye, and the data will be compared between operated and fellow eye and with the other group.

NCT ID: NCT05480098 Recruiting - Ptosis, Eyelid Clinical Trials

Brimonidine for Intraoperative Hemostasis

Start date: May 26, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to observe and report the effects of topical ophthalmic brimonidine in oculofacial plastic surgery.

NCT ID: NCT01616108 Recruiting - Strabismus Clinical Trials

Bupivacaine Injection of Eye Muscles to Treat Strabismus

Start date: April 2012
Phase: Phase 2/Phase 3
Study type: Interventional

This study seeks to determine if bupivacaine injection of eye muscles can make them stronger and stiffer, and thereby correct the position of eyes that are turned in or mis-aligned, a condition generally termed strabismus. It seeks further to find out the different effects of various concentrations or formulations of bupivacaine, and whether addition of Botox to other eye muscles can add to the effect of bupivacaine and enhance the correction of strabismus.