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Psoriasis clinical trials

View clinical trials related to Psoriasis.

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NCT ID: NCT03322137 Completed - Psoriasis Vulgaris Clinical Trials

Safety, Efficacy, and Tolerability of SNA-120 in Subjects With Pruritus Associated With Psoriasis Vulgaris

Start date: October 10, 2017
Phase: Phase 2
Study type: Interventional

To characterize the efficacy, safety and tolerability of SNA-120 at 2 doses versus placebo when administered topically for the treatment of pruritus associated with psoriasis vulgaris (PV) and PV itself.

NCT ID: NCT03316781 Completed - Plaque Psoriasis Clinical Trials

Study of Efficacy and Safety of HLX03 in Subjects With Moderate to Severe Plaque Psoriasis

Start date: October 27, 2017
Phase: Phase 3
Study type: Interventional

This is a multicenter, randomized, double-blind, positive drug parallel-group controlled clinical study in China to evaluate efficacy, safety, tolerability and immunogenicity of HLX03 and adalimumab (Humira) in subjects with moderate to severe plaque psoriasis. This study will recruit 216 subjects (18-75 years old, male and female) with moderate to severe plaque psoriasis. The 216 subjects will be randomly assigned per 1:1 ratio into the following two treatment groups (HLX03 OR Adalimumab). The study will be conducted in three periods, including the screening period, treatment period and follow-up period. For each participating subjects, the maximal length of the study will be 56 weeks (including up to four weeks of screening time).

NCT ID: NCT03308799 Completed - Psoriasis Vulgaris Clinical Trials

A Clinical Trial Evaluating Efficacy and Safety of MC2-01 Cream

Start date: October 3, 2017
Phase: Phase 3
Study type: Interventional

This trial is a randomized, investigator-blind, multicentre, vehicle- and comparator-controlled, parallel-group trial with the purpose of evaluating efficacy, safety and convenience of the MC2-01 cream.

NCT ID: NCT03284879 Completed - Psoriasis Clinical Trials

Post-Marketing Surveillance Study of OTEZLA

Start date: September 5, 2017
Phase:
Study type: Observational

To evaluate the safety and efficacy of OTEZLA in actual clinical settings of use in patients with Psoriasis vulgaris that is with an inadequate response to topical therapies and Psoriasis arthropathica 1. Planned registration period 2 years 2. Planned surveillance period for 4 years from 6 months after launch

NCT ID: NCT03279978 Completed - Healthy Clinical Trials

This Study Tests How Healthy Men Tolerate Different Doses of BI 730357 and How the Metabolism of Midazolam is Affected by BI 730357

Start date: January 9, 2018
Phase: Phase 1
Study type: Interventional

Phase Ib evaluation of the safety, tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) properties of Multiple Rising Dose (MRD) administration of BI 730357 to healthy volunteers for up to 28 days.

NCT ID: NCT03265613 Completed - Psoriasis Clinical Trials

Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis

ADMSP
Start date: September 24, 2017
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of Adipose-derived Mesenchymal Stem Cells (AD-MSCs) with moderate to severe psoriasis. Any adverse events related to AD-MSCs infusion will be monitored. Safety is assessed using incidence of Adverse Events(AEs) and Serious Adverse Events (SAEs). Efficacy is assessed via the proportion of the improvement of PASI (Psoriasis Area and Severity Index), relapse rate in treatment period, changes in PASI score and BSA, as well as DLQI.

NCT ID: NCT03262727 Completed - Psoriasis Clinical Trials

The Effect of BMS-986165 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients

Start date: September 1, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to investigate the effect of BMS-986165 in combination with an oral contraceptive in healthy female patients.

NCT ID: NCT03255382 Completed - Psoriasis Clinical Trials

A Study to Assess the Efficacy of Risankizumab Compared to FUMADERM® in Subjects With Moderate to Severe Plaque Psoriasis Who Are Naïve to and Candidates for Systemic Therapy

Start date: August 22, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of subcutaneous (SC) risankizumab and oral FUMADERM provided as study medication in participants with moderate to severe plaque psoriasis who are naïve to and candidates for systemic therapy.

NCT ID: NCT03254784 Completed - Psoriasis Clinical Trials

A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation

Start date: September 13, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate BMS-986165 tablet formulation versus BMS-986165 capsule formulation. This study will also evaluate the effect of a high-fat/ high-calorie meal and increased gastric pH on the BMS-986165 tablet formulation.

NCT ID: NCT03253666 Completed - Melanoma Clinical Trials

Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)

Start date: January 2017
Phase:
Study type: Observational [Patient Registry]

To determine the relationships of dietary factors with the subsequent risk of dermatological diseases (such as skin cancers and inflammatory or autoimmune dermatoses) in a cohort of female registered nurses and male health professionals.