The Endothelial Count in Pxf

Pseudoexfoliation Syndrome Clinical Trial

Official title:

The Corneal Endothelial Cell Count in Eyes With Pseudoexfoliation Syndrome

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03265457
• Other study ID #: PXF
• Status: Not yet recruiting
• Start date: October 1, 2018
• Est. completion date: October 1, 2020

Study information

• Verified date: June 2018
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.

Description:

The corneal Endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency.

In patients with pseudoexfoliation syndrome , quantitative and qualitative morphological changes of the corneal endothelium have been demonstrated in specular and electron microscopic studies.

Specular microscopy is a non-invasive technique to access the structure and function of the corneal endothelium.

Our research question is to study Endothelial cell count in patients with pseudoexfoliation syndrome & compare it to age matched group.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 20
• Est. completion date: October 1, 2020
• Est. primary completion date: October 1, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Patients with pseudoexfoliation syndrome

Exclusion Criteria:

• Patients with previous intra ocular surgeries.

• Patients with uveitis

• Patients with fuck's endothelial dystrophy

Related Conditions & MeSH terms

• Exfoliation Syndrome
• Pseudoexfoliation Syndrome
• Syndrome

Intervention

Other:
• Specular microscopy
Comparison between corneal Endothelial count in patients with pseudoexfoliation syndrome and age matched group

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

References & Publications (1)

Miyake K, Matsuda M, Inaba M. Corneal endothelial changes in pseudoexfoliation syndrome. Am J Ophthalmol. 1989 Jul 15;108(1):49-52. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Comparison between endothelial cell count in patients with Pseudoexfoliation syndrome and age matched controls.	The corneal Endothelial cell count in patients with pseudoexfoliation syndrome will be measured by the specular microscopy & compared with the normal endothelial count in people at the same group	One year