Pruritus Clinical Trial
Official title:
Randomized Prospective Open-label Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis
Many clinical studies have shown the benefit of music therapy in various pathologies,
including pain, and it is now established that the latter has a complementary therapeutic
interest. Its most frequently identified indications are the fight against acute or chronic
pains, the reduction of anxiety, depression and stress, as well as memory disorders such as
Alzheimer's disease.
The main modes of action of music therapy involve sensory, cognitive, psychological and
behavioral processes that are also found in pruritus.
Pruritus is defined as "an uncomfortable sensation causing the need to scratch. It has
similarities with pain but also differences: relief by heat / cold, scratching / withdrawal
behavior, localization on the skin, semi-mucous / ubiquitous ... etc.
The pathophysiology also has similarities, pruritus is born at the dermal-epidermal junction
at the level of specific cutaneous receptors then follows the classical pathways through a
1st neuron, then the dorsal horn of the spinal cord and a second neuron. At the cerebral
level, there is no single center of pruritus but several motor and sensory areas involved.
The similarities suggest that music therapy may have an interest in the management of chronic
pruritus, especially since classical treatments (antihistamines, topical corticosteroids)
have only partial efficacy in some dermatoses
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