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Clinical Trial Summary

To investigate the potential efficacy of dupilumab in the treatment of moderate to severe chronic hepatic pruritus.


Clinical Trial Description

This is a 22-week (2 week screening, 18-week treatment period followed by a 2 week followup), phase II, open label, exploratory study to investigate the potential efficacy of FDA approved dupilumab in the treatment of adults with moderate to severe chronic hepatic pruritus. Subjects will be screened at outpatient clinic visit appointments and interested qualified subjects will be consented and offered participation in this trial. Once consent has been obtained, baseline values will be established and subjects will begin treatment and follow-up for the next 20 weeks. A final visit will be needed for evaluation and questionnaire completion. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04256759
Study type Interventional
Source Mayo Clinic
Contact Rachel A Pung Page
Phone 904-953-8513
Email White.Rachel2@mayo.edu
Status Recruiting
Phase Phase 2
Start date September 1, 2020
Completion date April 2024

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