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L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain

Inflammation Clinical Trial

Official title:
High-concentration L-menthol as a Counter-irritant to TRPA1-induced Neurogenic Inflammation, Thermal and Mechanical Hyperalgesia Caused by Trans-cinnamaldehyde

Clinical Trial Summary

The aim of this study is to quantitatively characterize the effects of L-menthol as a topical counter-irritant on cutaneous pain and hyperalgesia provoked by topical application of the TRPA1-agonist trans-cinnamaldehyde (CA) in healthy human volunteers.

Clinical Trial Description

This study is designed as an experimental model in healthy humans. ;

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02653703
Study type Interventional
Source Aalborg University
Contact
Status Completed
Phase N/A
Start date October 2014
Completion date December 2014
View Details
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