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Prostate clinical trials

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NCT ID: NCT06364865 Enrolling by invitation - Acute Cholecystitis Clinical Trials

AE05ML Device for ML Hem-o-lok Polymer Clip Delivery in Laparoscopic Surgical Procedures Observational Registery Study

AE05ML
Start date: June 7, 2024
Phase:
Study type: Observational [Patient Registry]

This clinical registry study aims to evaluate the safety and effectiveness of the AE05ML device for ligating vessels and tissue structures during laparoscopic surgery using Hem-o-lok® Medium Large (ML) polymer clips. The primary objective is to assess the device's safety and performance, with secondary objectives focusing on device performance characteristics and operator feedback.

NCT ID: NCT06192758 Suspended - Cancer Clinical Trials

First In Human Dose Escalation Study Evaluating Safety of TheraSphere Prostate Cancer (PCa) Device

VOYAGER
Start date: April 15, 2024
Phase: N/A
Study type: Interventional

The VOYAGER Study is an interventional, non-randomized, single-arm, dose escalation trial with the goal of determining the safety of TheraSphere PCa device in patients with clinically localized prostate cancer across US-based centers.

NCT ID: NCT05509114 Completed - Prostate Clinical Trials

The Effect of Virtual Reality Glasses Application on Pain, Anxiety, and Patient Satisfaction

Start date: December 25, 2021
Phase: N/A
Study type: Interventional

The study was conducted in a randomized controlled manner to determine the effect of applying virtual reality glasses during transrectal prostate biopsy on pain, anxiety and patient satisfaction.The study was completed with a total of 70 patients, 35 in the intervention group and 35 in the control group, for whom it was decided to perform sample transrectal prostate biopsy for the first time.

NCT ID: NCT04518072 Recruiting - Cancer Clinical Trials

Synthetic Metabolic and Genetic Networks for Medical Diagnosics

SynBioDiag
Start date: January 6, 2021
Phase:
Study type: Observational

This is a category 3 human study, prospective, comparative, in parallel groups. A comparative qualitative and quantitative analysis of several markers in 250 samples is proposed.

NCT ID: NCT04377152 Approved for marketing - Prostate Cancer Clinical Trials

Expanded Access 68Gallium-PSMA-11 PET for Prostate Cancer

Start date: n/a
Phase:
Study type: Expanded Access

This expanded access protocol provides eligible participants with investigational 68Ga-PSMA-11 PET imaging to detect and localize prostate cancer for initial and subsequent treatment strategy.

NCT ID: NCT03318367 Terminated - Prostate Clinical Trials

Virtual Reality Education Module in Reducing Anxiety and Increasing Knowledge in Patients With Prostate Cancer Undergoing Radiation Therapy

Start date: August 6, 2014
Phase: N/A
Study type: Interventional

This pilot clinical trial studies a virtual reality education module in reducing anxiety and increasing knowledge in patients with prostate cancer undergoing radiation therapy. A virtual reality education module may be useful in helping patients understand what they can expect to happen during their radiation treatments and help reduce stress relating to the radiation treatments.

NCT ID: NCT03197948 Terminated - Prostate Clinical Trials

Electronic Patient Reported Outcomes in Measuring Health-Related Quality of Life in Patients With Stage I-IV Prostate Cancer Undergoing Treatment

Start date: July 28, 2016
Phase:
Study type: Observational

This pilot clinical trial studies how well electronic patient reported outcomes work in measuring health-related quality of life in patients with stage I-IV prostate cancer undergoing treatment. Using a smartphone application to measure and monitor symptoms before, during, and after treatment may help patients better detect, understand, and manage their health.

NCT ID: NCT03197896 Active, not recruiting - Prostate Clinical Trials

Educational Intervention in Increasing Knowledge About Prostate Cancer in High-Risk Neighborhoods

Start date: September 29, 2016
Phase: N/A
Study type: Interventional

This clinical trial studies how well an educational intervention works in increasing knowledge about prostate cancer in high-risk neighborhoods. Learning about prostate cancer and the pros and cons of screening for prostate cancer may increase knowledge about prostate cancer while decreasing anxiety and concerns about prostate cancer screening.

NCT ID: NCT03047135 Active, not recruiting - Prostate Clinical Trials

Olaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With Integrated Biomarker Analysis

Start date: March 1, 2017
Phase: Phase 2
Study type: Interventional

Olaparib has demonstrated preliminary efficacy in metastatic castration-resistant prostate cancer. In a trial of 49 evaluable patients treated with olaparib, 11 / 49 experienced a PSA response, and every patient with a radiographic response also had a PSA5 response. Ten of 11 responders had mutations in DNA repair genes. While PARP inhibition is showing promise in these initial studies, reserving its use for end-stage patients may not be the optimal timing for olaparib therapy in some patients. In addition, PARP enzymes function in roles beyond DNA repair, and specifically for prostate cancer are involved transcriptional regulation of the androgen receptor. PARP inhibition has not been tested in earlier disease states for prostate cancer.

NCT ID: NCT02918227 Terminated - Clinical trials for Benign Prostatic Hyperplasia

Exploration of Ejaculation Changing Mechanism After Surgery for Benign Prostatic Hyperplasia

EMMECH
Start date: December 8, 2016
Phase: N/A
Study type: Interventional

Every year in France, more than 60 000 people are operated for benign prostatic hyperplasia (BPH). This surgery is accompanied by a change or even a loss of ejaculations externalized what constitutes the main constraint for patients. Empirically, the investigators talk to the patient "retrograde ejaculation" to explain a possible loss of ejaculation. Yet the underlying mechanism of this modification or loss of ejaculation remains completely unknown. Yet the underlying mechanism of this modification or loss of ejaculation remains completely unknown. No study could not determine whether the predominant mechanism was a real retrograde ejaculation or aspermia. Moreover, technical changes are sometimes tempted to preserve antegrade ejaculation but no scientific rationale can not validate.