Prognosis Clinical Trial
Official title:
A Cohort Study on the Outcome and Influencing Factors of High-risk Pregnant Women With Perinatal Depression in the Third Trimester
1. Research and follow-up of the course and outcome of high-risk pregnant women with
perinatal depression in the third trimester;
2. Factors affecting the outcome of the disease;
3. Recurrence of PND in pregnancy again;
4. The influence of different intervention methods on the course of the disease.
Research objectives
1. Research and follow-up of the course and outcome of high-risk pregnant women with
perinatal depression in the third trimester;
2. Factors affecting the outcome of the disease;
3. Recurrence of PND in pregnancy again;
4. The influence of different intervention methods on the course of the disease. Research
process: 1. The pregnant women who were filed at Xinhua Hospital and Tongji Hospital and
were receiving perinatal care from July 2019 to December 2019 were evaluated in the
third trimester of pregnancy using the General Situation Questionnaire, SSRS, PHQ-9, and
GAD-7. Those with PHQ-9 score ≥ 5 or GAD ≥ 5 were classified as having symptoms of
depression and anxiety, and those who were screened positive were included in the study
cohort; 42 days postpartum, 3 months postpartum, 6 months postpartum, 12 months
postpartum, 18 months postpartum , 24 months postpartum, use PHQ-9, GAD-7 scale, 6
quality of life questionnaires, and SSRS to evaluate the cohort. If the PHQ-9 score is
greater than or equal to 5 or the GAD is greater than or equal to 5, the psychiatrist
will perform a clinical examination based on DSM-IV to make a clinical diagnosis; the
outcome of the cohort and the incidence and influencing factors; 2 . During the
follow-up process, the cohort developed high-risk pregnant women with depression,
anxiety symptoms and other perinatal depressive disorders during the follow-up process.
Based on the WeChat platform, integrated general hospitals, psychological counseling
centers, social families and other service resources were carried out throughout the
prenatal and first delivery period. Intervention methods such as community intervention
for perinatal depression that focus on the comprehensive "physiology, psychology, and
society" of the whole process after the first childbirth. Pregnant women diagnosed with
PND will be evaluated by a psychiatrist to determine the treatment plan, and follow-up
will continue.
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