Language in Primary Progressive Aphasia

Status Recruiting

Clinical Trial Summary

The purpose of this study is to further define the neurological and linguistic deterioration in primary progressive aphasia.

Clinical Trial Description

The Language in Primary Progressive Aphasia (PPA) aims to understand the behavioral, anatomical and physiological changes in people with PPA throughout the course of the illness. The researchers in this study want to increase awareness of PPA, educate others about this unique disorder, and to encourage more research to eventually develop therapies. During the three-day research program, participants will be asked to undergo neuropsychological testing (paper and pencil tests that evaluate cognition), advanced imaging (MRI and PET), cognitive experiments, and other computer and language testing batteries. Participants may be asked to return every two years to complete the same measures. For participants not living near Chicago, IL, flights and accommodations (for both the person with PPA and their companion) will be covered by the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00537004
Study type	Observational
Source	Northwestern University
Contact	Seyi Adeolu
Phone	312-503-2398
Email	PPA.Research@northwestern.edu
Status	Recruiting
Phase
Start date	May 2007
Completion date	April 2027

View Details

See also
Status	Clinical Trial	Phase
Suspended	`NCT04290988` - Circuitry Assessment and Reinforcement Training Effects on Recovery	N/A
Recruiting	`NCT04957537` - Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia	N/A
Completed	`NCT04045990` - Network Modulation in Alzheimer's Disease	N/A
Recruiting	`NCT05443633` - Enhancing Language Function in Aphasia	N/A
Active, not recruiting	`NCT05860647` - Transmagnetic Stimulation Pilot in Primary Progressive Aphasia	N/A
Recruiting	`NCT03887481` - Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA	N/A
Completed	`NCT03728582` - Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy	N/A
Completed	`NCT01465360` - Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center	N/A
Completed	`NCT02541097` - Preventing Language Decline in Dementia	N/A
Recruiting	`NCT05741853` - Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia	N/A
Active, not recruiting	`NCT05742698` - Nabilone for Agitation in Frontotemporal Dementia	Phase 2
Completed	`NCT02439853` - Communication Bridge Speech Therapy Research Study	N/A
Completed	`NCT01623284` - PiB PET Scanning in Speech and Language Based Dementias	Phase 1
Completed	`NCT04726527` - Clinical Evaluation of Florbetapir in Primary Progressive Aphasia
Completed	`NCT03076671` - More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease	N/A
Completed	`NCT05537688` - Identification of Graphic Markers of Neurocognitive Disorders (MG)
Completed	`NCT05525377` - Better Living With Non-memory-led Dementia	N/A
Not yet recruiting	`NCT06191198` - Communication Bridge 3 Study	Phase 2
Completed	`NCT02928848` - Transcranial Direct Current Stimulation for Primary Progressive Aphasia	N/A
Completed	`NCT04939818` - Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders