Prevalence of and Factors Associated With Reventilation Syndrome (DS) Clinical Trial
Official title:
Prevalence and Risk Factors of Dreentilation Syndrome in a Population of Patients Under Ventilation for Whatever Reason
Non-invasive nocturnal ventilation is an effective treatment for chronic respiratory
failure, whether due to obstructive (COPD), restrictive or neuromuscular causes, notably for
patients in the last two categories for whom it significantly prolongs life expectancy.
Overall, the treatment is well tolerated, its principal adverse effects being discomfort
related to the mask.
In certain patients, morning dyspnoea when the mask is removed has been described. This is
disabling as it limits everyday activities for at least 30 minutes, and defines
deventilation syndrome. The pathophysiology of this syndrome is uncertain, notably the roles
of hyperinflation, patient/ventilator asynchrony, or the sudden increase in diaphragmatic
work after a night of rest.
The aim of this study is to investigate the prevalence of and factors associated with
reventilation syndrome (DS) in a population of patients with ventilation whatever the
reason, in a stable state, and followed by the medical devices department of Dijon CHU, so
as to better understand the mechanisms. Patients with DS will subsequently be invited to
participate in a therapeutic trial.
n/a
Observational Model: Case Control, Time Perspective: Prospective