Evolution of Sexual Life Quality of Women With POI Before and After Introduction of Hormone Replacement Therapy — SEX-POInt  

Premature Ovarian Failure Clinical Trial

Official title: Evolution of Sexual Life Quality of Women With POI Before and After Introduction of Hormone Replacement Therapy

Status Recruiting

Clinical Trial Summary

The aim of this study is to evaluate the evolution of quality of sex life of women with POI after introduction hormone replacement therapy through the FSFI scale

Clinical Trial Description

Premature ovarian failure (POI) is a pathology that affects about 1-2% of women before the age of 40. The resulting estrogen deficiency is the cause of multiple repercussions. Clinically, sexual disorders may appear in the short term, such as a decrease in libido, vaginal dryness, an increase in dyspareunia, resulting in less frequent sexual intercourse and less satisfaction with sexual life. The quality of life of these patients also appears to be reduced compared to women with normal ovarian reserve. A 2008 study showed that the sexual function of patients with POI treated with hormone replacement therapy (HRT) was normal but remained significantly lower than that of patients with normal ovarian function. However, no study has attempted to assess the evolution of the symptomatology of these patients before and after the introduction of HRT. Evidence of improvement in sexual disorders under treatment could be an additional argument to improve patient adherence and treatment compliance; as well as information for health professionals ;

Related Conditions & MeSH terms

• Menopause, Premature
• Premature Ovarian Failure
• Primary Ovarian Insufficiency

• NCT number: NCT05890417
• Study type: Interventional
• Source: University Hospital, Bordeaux
• Contact: Valerie Bernard, MD
• Phone: -335 56 79 56 79
• Email: valerie.bernard@chu-bordeaux.fr
• Status: Recruiting
• Phase: N/A
• Start date: July 17, 2023
• Completion date: June 2025