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Pregnancy clinical trials

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NCT ID: NCT01948258 Completed - Pregnancy Clinical Trials

Clearblue Advanced Fertility Monitor Consumer One Cycle at Home Study

Start date: March 1, 2013
Phase: N/A
Study type: Interventional

This study will assess the use of the new Clearblue Advanced Fertility Monitor for one menstrual cycle in a home setting by female volunteers seeking to get pregnant.

NCT ID: NCT01945424 Completed - Pregnancy Clinical Trials

Sanofi Pasteur Quadrivalent Influenza Vaccine (QIV) Pregnancy Registry

Start date: August 16, 2013
Phase:
Study type: Observational [Patient Registry]

The Sanofi Pasteur Quadrivalent Influenza Vaccine (QIV) Pregnancy Registry will be a prospectively recruited pregnancy surveillance program designed to collect and analyze information on vaccine exposures, pregnancy outcomes, and fetal and offspring outcomes.

NCT ID: NCT01944787 Not yet recruiting - Pregnancy Clinical Trials

Hydration and Rate of Cesarean Delivery Among Nulliparous

Start date: September 2013
Phase: N/A
Study type: Interventional

The hypothesis of the present study is the hydration of nulliparous women with 250ml/hour vs. 125ml/hrs would decrease the rate of primary cesarean section.

NCT ID: NCT01936610 Completed - Pregnancy Clinical Trials

the Effect of Instructional Method on Decision Making

Start date: June 2010
Phase: Phase 2/Phase 3
Study type: Interventional

In these single- blind clinical trial 67 primigravida females, gestational aged 34-36 week were selected using multi-stage sampling and assigned into two groups randomly. Decision-making (before, two weeks after and at admission in maternity department) was tested by a researcher -made questionnaire. In experiment group, advantages and disadvantages of normal delivery and cesarean-section delivery were presented by role-playing in three 90-min scenarios. It was also presented in a 90-min lecture. Data were analyzed using SPSS by mean difference test, exact fisher test, independent t-test and paired t-test.

NCT ID: NCT01932138 Completed - Pregnancy Clinical Trials

Trial to Improve Access to PMTCT Services and Reduce HIV Transmission From Mother to Child

FS
Start date: January 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effectiveness, cost-effectiveness, feasibility and acceptability of an enhanced community health worker (CHW) intervention and outreach system to improve antenatal care and PMTCT uptake and retention, and to decrease mother-to-child HIV transmission.

NCT ID: NCT01931280 Completed - Pregnancy Clinical Trials

A Transgenerational e-Intervention for Gestational Diabetics and Their Offspring

GooD MomS
Start date: September 2013
Phase: N/A
Study type: Interventional

This study includes a behavioral educational intervention that focuses on healthy eating, physical activity and glucose management during pregnancy and post partum among women newly diagnosed with gestational diabetes mellitus (GDM).

NCT ID: NCT01924013 Completed - Pregnancy Clinical Trials

Maternal Vitamin D for Infant Growth (MDIG) Trial

MDIG
Start date: March 2014
Phase: Phase 3
Study type: Interventional

The primary aims of this study are: 1) to determine whether maternal prenatal vitamin D3 supplementation (4200 IU/week, 16,800 IU/week, or 28,000 IU/week) versus placebo increases or decreases infant length at 1 year of age, and 2) to determine whether maternal postpartum vitamin D3 supplementation (28,000 IU/week) versus placebo increases or decreases length at 1 year of age among infants born to women who received vitamin D 28,000 U/week during pregnancy. Infants enrolled in the study will be followed for 2 years to document the persistence of any observed effects measured at 1 year of age. This study aims to enroll 1300 pregnant women in the 2nd trimester at a maternity hospital in Dhaka. Participants will be randomized to one of three doses of vitamin D3 (4200 IU/week, 16,800 IU/week, or 28,000 IU/week) or placebo throughout pregnancy. Women in the 28,000 IU/week group will be additionally randomized to either placebo or a continuation of 28,000 IU/week for 6 months postpartum. In addition to linear length, the trial will include analyses of inflammatory and hormonal determinants of infant growth, epigenetic phenomena that affect vitamin D metabolism, and diarrheal and respiratory morbidity in the infants.

NCT ID: NCT01922791 Completed - Obesity Clinical Trials

Nutrition and Pregnancy Intervention Study

Start date: October 2013
Phase: N/A
Study type: Interventional

A randomized double-blind placebo controlled intervention study with pregnant obese women (n=440) will be conducted. The intervention will involve consumption of fish oil and/or probiotic capsules from early pregnancy until 6 months after delivery. The aim of the study is firstly to investigate the effects of the supplements on the risk of gestational diabetes mellitus and obesity in the women and secondly to modify the risk markers of allergy and obesity in children of the women. Also the underlying metabolic mechanisms will be investigated. Follow up visits at child's age of 5 to 6 years will be conducted to evalute long-term effects on maternal and child health. The aim is to investigate the impact of dietary intervention, diet, maternal overweight/obesity and gestational diabetes status as well as gut microbiota and metabolism during pregnancy on maternal and child's health, allergy and child neuropsychological development.

NCT ID: NCT01917799 Recruiting - Pregnancy Clinical Trials

Aspirin, Heparin and Miscarriage

Start date: January 2009
Phase: Phase 4
Study type: Interventional

Efficacy of low dose aspirin (LDA) versus LDA plus low-molecular-weight-heparin (LMWH) in patients with a history of recurrent miscarriages.

NCT ID: NCT01916694 Completed - Pregnancy Clinical Trials

Trial of Remote Evaluation and Treatment of Gestational Diabetes Mellitus

TREAT-GDM
Start date: September 2013
Phase: N/A
Study type: Interventional

Diabetes in pregnancy (gestational diabetes) is becoming more common. It can lead to problems for both mothers-to-be and their babies such as causing a large baby and difficult birth. Gestational diabetes in the mother may also lead to effects on the long term health of the baby. Most people today use mobile phones. Our research is looking at using a mobile phone app to help with diabetes care in pregnancy. In particular, the investigators are using phones which connect to the standard blood glucose monitoring machines given to all women with gestational diabetes to see if sending the hospital team blood test results between clinic appointments can result in the need for fewer clinic visits. The investigators are also testing to see how acceptable using mobile phones in this way, is to our patients and that the control of the blood glucose and outcomes for the mother and baby are at least as good as standard care. The investigators are planning to recruit 200 women who receive care for their gestational diabetes at the Oxford University Hospitals NHS (National Health Service) Trust. They will be randomised so that 100 will receive standard care, and 100 will have a mobile phone "app" linked to the blood glucose machines to send blood glucose readings directly to the diabetes care team to review. Both groups will be asked to test their blood glucose levels at home regularly with a glucometer. All participants will also be given lifestyle advice to reduce the chance they will need medication. Blood glucose control will be measured also by the percentage of glycated hemoglobin (HbA1c) at the time of diagnosis of gestational diabetes and before delivery.