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Pregnancy clinical trials

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NCT ID: NCT02512913 Completed - Pregnancy Clinical Trials

Family Smoking Cessation in Romania Using Pregnancy as a Window of Opportunity

QuitTogether
Start date: November 25, 2015
Phase: N/A
Study type: Interventional

The purpose of this research is to adapt and implement a pregnancy and postnatal smoking cessation intervention for couple that will begin early in pregnancy and have an additional postnatal component.

NCT ID: NCT02510534 Terminated - Pregnancy Clinical Trials

Effect of Luteal Progesterone Support on Pregnancy Rates With Combined Clomid/ Gonadotropin & IUI

Start date: July 2015
Phase: Phase 1
Study type: Interventional

To determine the difference in clinical pregnancy rates with and without luteal progesterone support in a young reproductive aged population having undergone ovulation induction with combined clomiphene citrate and gonadotropin protocol with intrauterine insemination.

NCT ID: NCT02509377 Terminated - Pregnancy Clinical Trials

Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0

MOMSto40BMI
Start date: July 2015
Phase: N/A
Study type: Interventional

Inclusion and exclusion criteria for fetal repair of MMC was established by the Management of Myelomeningocele Study (MOMS Trial) and these criteria are the standard of care throughout the United States. These criteria state exclusion for hypertension and diabetes which are known co-morbidities for obesity. Investigators plan to expand one exclusion criteria for open fetal repair surgery. Currently, an exclusion factor is a maternal BMI of 35.0 and greater.Investigators will maintain all other inclusion and exclusion criteria (including excluding for hypertension and diabetes) with the exception of expanding the BMI to include mothers with a BMI of 35.0 to 40.0. Co-morbidities of the research group will be compared to the comorbidities of the mothers published in the MOMS trial.

NCT ID: NCT02508844 Completed - Obesity Clinical Trials

Effect of Probiotics (Vivomixx®) on Weight, Microbiota and Glucose Tolerance in Obese Pregnant Women and Their Newborn

POP
Start date: April 2015
Phase: Phase 4
Study type: Interventional

The purpose of the study is to investigate if the probiotics Vivomixx® can affect gestational weight gain, microbiota and pregnancy complications in pregnant obese women and birth weight body composition of their infants.

NCT ID: NCT02508779 Completed - Pregnancy Clinical Trials

BGAT (Blood Glucose Awareness Training) for Users Who Might Become Pregnant

Bump2Be
Start date: July 2015
Phase: N/A
Study type: Interventional

Ineffective management of blood glucose (BG) levels during preconception and pregnancy has been associated with severe maternal and fetal complications in women with type 1 diabetes (T1DM). Preconception care emphasizing stringent glycemic control in the preconception period and continued through early pregnancy can dramatically reduce these risks. However, the use of preconception care in the US has been disappointingly low due to a variety of organizational, provider, and patient centered factors. Furthermore, efforts to achieve tight glycemic control can increase the risk of severe hypoglycemia (SH) in T1DM women, potentially leading to serious health consequences. In this project, the investigators will test an education based Internet intervention (Bump2be or Blood glucose awareness training (BGAT) for users who might become pregnant) for use with T1DM women who are either actively trying to become pregnant (TP) or planning to become pregnant in the 12 months following their enrollment in this study (PP). The main objective is to examine Bump2be's feasibility and preliminary efficacy as an intervention for these women to better regulate their BG levels and to meet their diabetes-related clinical targets for pregnancy. More specifically, Bump2be will be tested in a randomized clinical trial in which 58 T1DM women who are either TP or PP will be recruited. As part of this pre-post study design, participants will be randomly assigned to either the Bump2be intervention (n=29) or the routine care group (n=29). Data collected will include frequency of extreme BG, consequences of extreme BG, average BG levels (HbA1c level), estimation of BG, detection of low and high BG, and psychological functioning (including fear of hypoglycemia, avoidance of hyperglycemia, well-being, and internal locus of control). Interviews with up to 10 trial participants will be conducted at the conclusion of their study participation, to enable further optimization of the intervention in preparation for a subsequent R01 submission. This will be the first study investigating the use of the Internet to improve detection and management of extreme BG levels in Diabetes mellitus type 1 (T1DM) women who are either TP or PP.

NCT ID: NCT02507180 Recruiting - Pregnancy Clinical Trials

Safely Ruling Out Deep Vein Thrombosis in Pregnancy With the LEFt Clinical Decision Rule and D-Dimer

LEaD
Start date: September 2015
Phase:
Study type: Observational

This is prospective cohort study in pregnant women who present with signs and symptoms of possible deep vein thrombosis (DVT). All patients will have the same method of assessment of their DVT symptoms (the LEFt clinical decision rule will be applied and D-dimer test will be done) to determine if a compression ultrasound is required. All patients will be followed for a period of 3 months.

NCT ID: NCT02506725 Active, not recruiting - Pregnancy Clinical Trials

Quarenta Semanas: Innovative Intervention in Prenatal Care for Reduction of Prematurity

quarenta
Start date: August 2015
Phase: N/A
Study type: Interventional

The goal of Quarenta Semanas is to remove risk factors for preterm birth by linking women to prenatal care in the first trimester; supporting, educating and empowering women in pregnancy to reduce maternal stress and interrupt social, psychological, attitudinal and biological risk factors for preterm birth; and providing evidence-based, quality care that identifies and intervenes medically to treat underlying chronic and emergent conditions associated with preterm birth.

NCT ID: NCT02505464 Recruiting - Pregnancy Clinical Trials

Pregnancies Complicated by Fetal Anomalies

FAR
Start date: May 2015
Phase:
Study type: Observational [Patient Registry]

The focus of this research is to create a repository of ultrasonographic images and their corresponding medical data from pregnant women (the mothers of the fetuses that are imaged), focusing on fetal anomalies. These women will visit the obstetrical clinics at Regional One Health and the Le Bonheur Fetal Center.

NCT ID: NCT02503995 Completed - Pregnancy Clinical Trials

Exercise in Pregnancy Evaluative Controlled Study

EXPECT
Start date: March 2012
Phase: N/A
Study type: Interventional

This study aimed to investigate whether there are measurable differences in CHANS function in pregnant women who receive only standard antenatal care compared with those who additionally undertake a programme of regular physical exercise.

NCT ID: NCT02497430 Completed - Pregnancy Clinical Trials

Clinical Evaluation of the ARIES Group B Streptococcus (GBS) Assay

Start date: March 2016
Phase: N/A
Study type: Observational

The ARIES GBS Assay is a real-time PCR based qualitative test designed to detect Group B Streptococcus (GBS) nucleic acid from Lim Broth enriched vaginal-rectal specimen swabs obtained from pregnant women between 35 - 37 weeks gestation.