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Pregnancy clinical trials

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NCT ID: NCT00782730 Completed - Pregnancy Clinical Trials

Assessment of Third Trimester Post-void Residual and Validation of Bladder Scanner in Pregnancy and Post-partum

Start date: October 2008
Phase: N/A
Study type: Observational

This will be a descriptive study measuring the post—void residual of patients in the third trimester and postpartum. Also, bladder scan values will be compared to the amount of urine obtained from a Foley catheter to determine the accuracy of the bladder scanner in the third trimester and postpartum.

NCT ID: NCT00779727 Terminated - Pregnancy Clinical Trials

Post-Cesarean Wound Drainage is Not Necessary in Women at Increased Risk of Hemorrhage

Start date: October 1999
Phase: Phase 4
Study type: Interventional

Randomized controlled trial assessing the benefit of cesarean wound drainage in pregnant women at increased risk of hemorrhage. The pregnant women at increased risk of hemorrhage were randomised in two groups. In one group 2 wound drainages were placed during the cesarean section, in the other group none. Outcome measures were difference between preoperative and postoperative hemoglobin, postoperative fever, cumulative opiate dose adjusted to body weight, length of stay and operation time. It is postulated that the pregnant women with increased risk of hemorrhage do not profit from the routine placement of wound drainages. - Trial with surgical intervention

NCT ID: NCT00774124 Completed - Diabetes Mellitus Clinical Trials

Improving Outcomes in Underserved Women With GDM

Start date: August 2007
Phase: N/A
Study type: Interventional

Our objective is to test an innovative approach to improve outcomes among underserved women with gestational diabetes. We ill utilize a multi-lingual, Interactive Voice Response (IVR) -enabled telephone system to facilitate diabetes control and thereby improve pregnancy outcomes. Our hypothesis is that Telemonitoring will improve maternal glycemia, thereby reducing infant birth weights and leading to improved pregnancy outcomes.

NCT ID: NCT00767338 Terminated - Pregnancy Clinical Trials

Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis

VIA
Start date: May 2010
Phase: Phase 3
Study type: Interventional

The primary research hypothesis is that microsurgical varicocelectomy will result in an increase in live birth in infertile couples where the male partner has a palpable varicocele and an abnormal semen analysis in comparison to male partners who do not have microsurgical varicocelectomy. The secondary hypotheses include: 1. To assess whether up to 4 cycles of intrauterine insemination confers any additional increase in live birth rates compared to timed intercourse; 2. To examine spousal pregnancy rate as the secondary outcome; and 3. To study the effect of varicocelectomy in men with infertility, an abnormal semen analysis, and a palpable varicocele on - Testicular semen analysis parameters; - Serological measures of FSH, LH, total and free testosterone and - Measures of quality of life and sexual function in both partners.

NCT ID: NCT00766818 Completed - HIV Clinical Trials

The Effect of Pregnancy on the Pharmacokinetics of the Kaletra Tablet

Start date: January 2007
Phase: Phase 1
Study type: Interventional

In this study, we are looking at blood concentrations of Kaletra in HIV positive patients during pregnancy. The patients will come in for 4 visits lasting ~24hrs. These visits take place at 20-24 weeks, 30 weeks, 32 weeks and 8 weeks post-partum. At the end of vist 2 (week 30), we will increase your dose to 2 adult Kaletra tablets, and one pediatric Kaletra tablet (total dose 500/125mg). The dose will remain increased until you are 2 weeks post partum, then it will return to the standard 2 adult tablets (400/100mg).

NCT ID: NCT00763672 Completed - Hypertension Clinical Trials

MorbiMortality Amelioration in Preeclamptic Primiparas Study. MoMA Pre Prim Study

MOMA
Start date: November 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether close monitoring of patients with a high sFlt1 plasma level between 25 and 28 weeks of gestation (i.e. at high risk of subsequent preeclampsia) improves maternal and fetal outcomes. The investigator hypothesize that 1/ early screening for preeclampsia by plasmatic sFlt1 will reduce maternal and fetal mortality and morbidity and 2/ a simple urinary PlGF screening will be effective.

NCT ID: NCT00759733 Withdrawn - Pregnancy Clinical Trials

Evaluation Cardiac Function With Echo and BNP in Obstetrical Patients With/Without Cardiac Disease

Start date: July 2008
Phase:
Study type: Observational

Maternal cardiac disease complicates approximately 2 percent of pregnancies and is the leading cause of non-obstetrical maternal death. Evaluating cardiac function and dysfunction is a complex process requiring skilled clinicians and technology such as ECG, long-term monitoring, and echocardiography. A fast, easily obtained blood test for B-type natriuretic peptide (BNP) has been developed that can give evidence for heart muscle stretch and dysfunction among adults with suspected congestive heart failure. Preliminary experience indicates that ventricular dysfunction among OB patients with a history of heart disease can be detected with this serum assay. A prospective cohort design consisting of two groups of pregnant patients; one with a history of cardiac disease and one without, will be followed over the course of the pregnancies and cardiac function will be measured using echocardiography and serum BNP. It is hoped that the blood test for BNP will be a reliable way to help evaluate OB patients with suspected abnormal heart function.

NCT ID: NCT00759278 Withdrawn - Hypertension Clinical Trials

Comparison Fetal Hemodynamic Measurements Antihypertensive Versus Control

Start date: August 2008
Phase:
Study type: Observational

This is a prospective case-control study to evaluate women who are pregnant and take antihypertensive medication for fetal hemodynamics (middle cerebral artery peak systolic flow and umbilical artery Doppler systolic to diastolic ratio) compared to a control group of pregnant women not taking these kinds of medications. The hypothesis is that the investigators expect to observe little to no difference in the comparison between the medication group and the control group.

NCT ID: NCT00741312 Completed - Pregnancy Clinical Trials

Influence of Physical Exercise on Endothelial Function in Pregnant Women

Start date: October 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the effect of regular aerobic exercise on endothelial function in pregnancy.

NCT ID: NCT00740506 Completed - Pregnancy Clinical Trials

Behavioral and Environmetal Factors and Time to Delivery

Start date: August 20, 2008
Phase: Phase 4
Study type: Interventional

This study, conducted at the Naval Medical Center in San Diego, CA, will determine if having vaginal intercourse in the last weeks of pregnancy decreases the risk of having a prolonged pregnancy. Pregnancies that continue beyond the due date may increase health risks for the mother and the baby. Although some believe that vaginal intercourse can help start labor in the last weeks of pregnancy, there is not proof that it works. Some studies showed that sexual intercourse helped and some that pregnancy lasted even longer for couples having sex. In addition to exploring the effect of sexual intercourse on time to delivery, this study will collect information that can be used in the future to predict when labor will naturally start and the risk for overdue pregnancies. Women 18 years of age and older in their first pregnancy who are carrying a single fetus with gestational age before 38 plus 6 weeks may be eligible for this study. Candidates must be living with their partner in a stable relationship. Participants are asked to have sexual intercourse about three times per week. They complete a diary in which they record the times they have intercourse and how they are feeling daily. The diaries are submitted by mail each week or at the doctor's or midwife's visit until delivery. The women have a pelvic exam and ultrasound and complete questionnaires about problems during pregnancy, overall well-being, attitude toward induction of labor, physical activity, body image during pregnancy, stress and social support, habits at home, and environmental conditions, such as weather.