Ideal Time of Oxytocin Infusion During Cesarean Section — I-TOPICS  

Pregnancy Related Clinical Trial

Official title: Ideal Time of Oxytocin Infusion During Cesarean Section

Status Terminated

Clinical Trial Summary

This study will evaluate if the timing of oxytocin administration in cesarean deliveries will affect the amount of maternal blood loss. Half of participants will receive oxytocin after delivery of the fetal anterior shoulder and the other half will receive oxytocin after delivery of the placenta. We hypothesize that administering oxytocin after delivery of the shoulder, will result in less overall maternal blood loss.

Clinical Trial Description

Oxytocin is a routinely administered medication for both vaginal and cesarean deliveries in the third stage of labor, as part of standard of care in the United States. This medication helps to reduce overall blood loss, by functioning as a uterotonic. Currently evidence is lacking to direct timing of oxytocin administration in cesarean deliveries.

This study will evaluate both estimated and quantitative blood loss for both groups of patients. It will also compare the change from pre-operative to post-operative hemoglobin levels. ;

Related Conditions & MeSH terms

• Bleed Pregnancy
• Blood Loss, Surgical
• Cesarean Section Complications
• Hemorrhage
• Postpartum Hemorrhage
• Pregnancy Related

• NCT number: NCT03246919
• Study type: Interventional
• Source: Loyola University
• Status: Terminated
• Phase: Phase 4
• Start date: September 13, 2017
• Completion date: February 24, 2020