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Pregnancy, Prolonged clinical trials

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NCT ID: NCT05840471 Completed - Vaginal Bleeding Clinical Trials

Tranexamic Acid as an Intervention in Abruptio Placenta

Start date: January 10, 2023
Phase: N/A
Study type: Interventional

Abruptio placenta is one of the common causes of antepartum haemorrhage which is more common in the second half of pregnancy and causes a high maternal and neonatal morbidity and mortality

NCT ID: NCT05511727 Not yet recruiting - Induction of Labor Clinical Trials

Use of Single Versus Double Foley's Catheter in Pre-induction Cervical Ripening

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Cervical ripening should be present before labor induction, which can generally be divided into two categories: pharmacological and mechanical

NCT ID: NCT04848701 Completed - Post Term Pregnancy Clinical Trials

Uterocervical Angle: a Screening Tool That Estimates the Latent Phase Duration in Post Term Pregnancies

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

To evaluate the performance of uterocervical angle (UCA) in the prediction of latent phase duration in post term pregnancies

NCT ID: NCT04744168 Completed - Clinical trials for Pregnancy Beyond 41 Week's Gestation

Acupuncture Effect on the Rate of Maturation in Post Term Pregnancies.

MATUPUNCTURE
Start date: March 9, 2021
Phase: N/A
Study type: Interventional

Brief Summary Short description of the protocol intended for the lay public. Include a brief statement of the study hypothesis. (Limit: 5000 characters) Example: The purpose of this study is to determine whether prednisone, methotrexate, and cyclophosphamide are effective in the treatment of rapidly progressive hearing loss in both ears due to autoimmune inner ear disease (AIED). The first purpose of this randomized study is to determine if five points of acupuncture : 4GI, 6RP, 34VB, 36E, 3F could improve the bishop score for prolonged pregnancies and decrease the rate of maturation. The protocol of our study consists of proposing to the pregnant women one or two acupuncture sessions the term's day and three days later. Once the consent is signed, women are randomly included in the experimental or placebo arm. In the experimental arm, midwives puncture five points : 4GI, 6 RP, 34VB, 36E, 3F on each side while in the placebo arm, they puncture just one point : 16 HM on each side. The maturation's rate between the two groups will be compared by a Fisher's exact test and analyzed in function parity (nulliparous or multiparous) and number of sessions (one or two) with a model of univariate and multivariate logistic regression.

NCT ID: NCT04451109 Enrolling by invitation - Clinical trials for Gestational Diabetes

Dilapan-S®: A Multicenter US E-registry

Start date: December 1, 2020
Phase:
Study type: Observational

Objective of this registry is to collect a representative set of real world data on the use of Dilapan-S® for pre-induction cervical ripening in daily clinical practice. Upon completion of the registry, relevant collected data will be analyzed and published.

NCT ID: NCT04307199 Not yet recruiting - Pregnancy Related Clinical Trials

Membrane Sweeping to Prevent Post-term Pregnancy: The MILO Study

MILO
Start date: July 30, 2020
Phase: N/A
Study type: Interventional

Multicentre, pragmatic, parallel group, pilot randomised controlled trial with an embedded factorial design.

NCT ID: NCT04299438 Terminated - Clinical trials for Pregnancy, Prolonged

Propranolol Rescue of Prolonged Labor

PROPEL
Start date: July 14, 2020
Phase: Phase 3
Study type: Interventional

A double-blind placebo controlled randomized trial comparing cesarean delivery rates in women given IV propranolol versus placebo for treatment of prolonged labor.

NCT ID: NCT04117308 Completed - Prolonged Pregnancy Clinical Trials

Analysis of the Use of the Fetal Movement Counting for Prolonged Pregnancy.

COMPTAMAF
Start date: October 3, 2019
Phase: N/A
Study type: Interventional

Prospective mono-centric randomized open-label study (randomization 1: 1, 2 groups) comparing a group of patients who received conventional information to a group of patients who had been sensitized to a fetal active movement count technique. The study will take place at the University Hospital Center of Saint-Etienne in the gynecology-obstetrics department. An information brochure on the study will be handed over at the end of the term consultation to 41+0 weeks of gestation. After collecting the consent of the patient, the distribution between the two groups will be done by randomization. Thus, for the fetal active movement count group, fetal active movement count education will be proposed during the term consultation with the submission of an information brochure. The "control" group will also receive a simple information pamphlet with, in writing, what patients currently receive orally: definition of active fetal movements, and the need to consult if the patient perceives less movements of her fetus .The principal objective is to compare perinatal morbidity in relation with the sensation of decrease active fetal movements in case of late pregnancy, according to the fact if the patients use or not the AFM's count.

NCT ID: NCT03607929 Recruiting - Pregnancy Clinical Trials

HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor

HYDRATA
Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Aim. To evaluate the efficacy of optimizing hydration during labor in nulliparous women with respect to reducing the duration of dilation and the second stage of labor, lowering the incidence of Cesarean sections and fever, and also with respect to changes in sodium and osmolarity in blood and urine, and 24 hour diuresis. Background. In the international scientific community there is a lack of consensus regarding the most suitable hydration strategies to be used in the attention of nulliparous women during low risk birth. Insufficient hydration during labor is associated with increased maternal and neonatal morbidity. Design. A randomized, controlled clinical trial with allocation concealment and masking during the evaluation of the results. Methods. A study of nulliparous women whose births and newborn are attended in the Obstetric Service of a University Hospital. The women will be randomized to two groups: the "optimal hydration" group, that will be guaranteed 300 ml/h (intravenous crystalloids and water) with a minimum diuresis of 400 ml/24h; and the "variability in hydration" group, comprised of the administration of intravenous and clear liquid volumes, without any established perfusion rate, based on criteria established by the healthcare professional attending the birth, and without established minimum diuresis. Mother outcomes: duration of labor, Cesarean section, fever, dehydration. Newborn outcomes: distress, hypoglycemia, hyponatremia, jaundice, weight loss in 48h, breastfeeding difficulties. Analysis will be per-protocol. Statistical significance will be set at p<0.05 Discussion. The findings obtained in this study will provide new evidence for considering the benefits of providing women with suitable optimized hydration during labor. Diminishing the clinical practice variability related to hydration strategies applied to nulliparous women attended during labor through the use of a decision-making algorithm to administer optimal hydration, would imply improved health and safety for mothers and their newborn together with reduced maternal and neonatal morbidity. Funding granted in 2015 by the Spanish Health Research Fund (PI 15/00897, Ministry of Health). Keywords: hydration; dehydration; adverse events; labor; Cesarean section, fever.

NCT ID: NCT03380897 Completed - Depression Clinical Trials

Sleep and Depression in Induction of Labour

Start date: June 7, 2017
Phase: N/A
Study type: Interventional

Randomised trial comparing double balloon catheter for induction of labor between inpatient and outpatient groups. The investigators assess how sleep disturbances and depression of the mother affect to the pain during balloon catheter induction of labour.