Investigation of the Serum Mucoprotein 3 (MUC3) Protein Levels in

Status Completed

Clinical Trial Summary

Clinical Trial Description

Hypertensive diseases of pregnancy are one of the most frequently encountered reasons for maternal and neonatal morbidity and mortality. The excretion of high levels of mucoprotein takes part in the pathogenesis of preeclampsia through restraining trophoblast invasion. This study aimed to investigate levels of serum mucoprotein three in hypertensive diseases of pregnancy. This study included a total of eighty cases that 20 normal pregnancy, 20 gestational hypertension, 20 preeclampsia, and 20 HELLP syndrome patients from June 2010- January 2011. This is the first study measuring levels of serum mucoprotein three in gestational hypertensive disease. MUC3 levels showed a distinctive increase in hypertensive diseases of pregnancy compared with the pregnant control group. As a result, it is found that plasma mucoprotein 3 levels increase as the severity of hypertensive diseases of pregnancy increases; and plasma mucoprotein 3 could be a precursor for the evaluation of the severity of the disease. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04421183
Study type	Observational [Patient Registry]
Source	Karadeniz Technical University
Contact
Status	Completed
Phase
Start date	June 1, 2010
Completion date	January 2, 2011

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Investigation of the Serum Mucoprotein 3 (MUC3) Protein Levels in Gestational Hypertensive Disease — MUC3

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms