Investigation of the Serum Mucoprotein 3 (MUC3) Protein Levels in

Status Completed

Clinical Trial Summary

Clinical Trial Description

Hypertensive diseases of pregnancy are one of the most frequently encountered reasons for maternal and neonatal morbidity and mortality. The excretion of high levels of mucoprotein takes part in the pathogenesis of preeclampsia through restraining trophoblast invasion. This study aimed to investigate levels of serum mucoprotein three in hypertensive diseases of pregnancy. This study included a total of eighty cases that 20 normal pregnancy, 20 gestational hypertension, 20 preeclampsia, and 20 HELLP syndrome patients from June 2010- January 2011. This is the first study measuring levels of serum mucoprotein three in gestational hypertensive disease. MUC3 levels showed a distinctive increase in hypertensive diseases of pregnancy compared with the pregnant control group. As a result, it is found that plasma mucoprotein 3 levels increase as the severity of hypertensive diseases of pregnancy increases; and plasma mucoprotein 3 could be a precursor for the evaluation of the severity of the disease. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04421183
Study type	Observational [Patient Registry]
Source	Karadeniz Technical University
Contact
Status	Completed
Phase
Start date	June 1, 2010
Completion date	January 2, 2011

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04286217` - SD-OCT Measurement of the Human Retina in Pregnancy With Pre-existing or De Novo Hypertension and Without Hypertension
Recruiting	`NCT04604535` - The BEET-BP Trial - Investigating the Effect of Dietary Nitrates on Hypertension in Pregnancy	N/A
Recruiting	`NCT04508582` - Cardiac and Immune Cell Function in Preeclampsia
Not yet recruiting	`NCT06248463` - Blood Pressure Assessment in Waiting Room During Pregnancy
Completed	`NCT01682304` - Epigenomic Dysregulation in Preeclampsia-Associated Chronic Hypertension
Suspended	`NCT01519297` - Preeclampsia: A Marker for Future Cardiovascular Risk in Women	N/A
Recruiting	`NCT02016638` - Sleep Quality in Pregnancy and Its Impact on Pregnancy Outcomes	N/A
Recruiting	`NCT05009433` - HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children	N/A
Withdrawn	`NCT00293735` - Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial	Phase 2/Phase 3
Recruiting	`NCT05434195` - Clinical Antenatal Randomised Study to CharactErise Key Roles of TetrahydroFOLate in HyperTensive Pregnancies	N/A
Suspended	`NCT04979793` - Role of L-citrulline in Prevention of Pregnancy Associated Hypertension	Phase 1
Recruiting	`NCT05955040` - Treatment of Elevated Blood Pressures in Early Pregnancy	Phase 2
Completed	`NCT04943133` - Concordance Between the Systolic Foot-to-Apex Interval and the Auscultatory Method for Measuring Brachial Systolic Pressure in Pregnant Women With or Without Blood Pressure Disorders and Search for Markers of Arterial Stiffness in Pre-eclampsia.	N/A
Not yet recruiting	`NCT02007837` - Prospects for the Prevention of Pregnancy-induced Hypertension and Preeclampsia Trial	Phase 3
Completed	`NCT02229526` - Fish Oil Trials in Pregnancy for the Prevention of Pregnancy Complications ('FOTIP')	N/A
Completed	`NCT03693638` - Fractionated Vs Single Dose Injection for Spinal C-Section in Patients With Pregnancy-Induced Hypertension	N/A
Completed	`NCT02213094` - Phase I Study of Nicotinamide for Early Onset Preeclampsia	Phase 1
Recruiting	`NCT06340152` - Multi-Omics for Maternal Health After Preeclampsia
Completed	`NCT05073978` - B-vitamin Levels and Adverse Pregnancy Outcomes
Completed	`NCT02468310` - Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana	N/A

Investigation of the Serum Mucoprotein 3 (MUC3) Protein Levels in Gestational Hypertensive Disease — MUC3

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms