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Pregnancy, Ectopic clinical trials

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NCT ID: NCT04325854 Completed - Clinical trials for Ectopic Pregnancy; Assisted Reproductive Technology

Risk Factors for Ectopic Pregnancy: Comparison of Fresh and Warmed Transfers. Analysis of a 10 Years, a Single Center Experience.

Start date: January 1, 2009
Phase:
Study type: Observational

Ectopic pregnancy (EP) is a leading cause of maternal death during the first trimester of pregnancy. Previous studies have reported an increased incidence of EP in Assisted reproductive technologies techniques (ART) (Clayton et al., 2006), and in particular with fresh blastocyst embryo transfer compared with warmed embryo transfer (Londra et al., 2015). In consideration of the widespread use of ART techniques in gynaecology and the high morbidity and mortality associated with EP, providing further insight into the risk factors associated with EPs in ART appears of great relevance. The objective of this study is to compare the incidences of EPs in all ART procedures (both I and II level) in a single, third level ART center throughout a 10-year period. In addition, we also aim to revise recognized EP's risk factors among patients undergoing these procedure and to evaluate their impact in determining extrauterine implantation

NCT ID: NCT04315779 Recruiting - Ectopic Pregnancy Clinical Trials

Comparison of Two Different Approaches in the Surgical Treatment of Tubal Ectopic Pregnancy

Start date: February 19, 2020
Phase: N/A
Study type: Interventional

In this study we aim to compare conventional laparoscopy and natural orifice transluminal endoscopic surgery in the surgical treatment of ectopic pregnancy. All the patients, with an indication of surgery for ectopic pregnancy, will be asked to participate in this clinical trial. Indication of surgery will be based on clinical findings, ultrasound scans and serum hcg levels. There will be no exclusion criteria. Duration of surgery, successful completion of the operation, intraoperative data and postoperative data will be collected. All the patients will be asked to fill out quality of recovery-40 (QoR-40) questionnaire and 36-item short form health survey (SF-36) before surgery. QoR-40 questionnaire will be repeated 24 hours after surgery and repeated every 24 hours until discharge. SF-36 will be repeated at 1-month follow-up visit. Patients will be also evaluated at postoperative 3-months, and female sexual function index will be asked to be filled-out.

NCT ID: NCT04308343 Not yet recruiting - Ectopic Pregnancy Clinical Trials

The Aromatase Inhibitor and Gnrh Antagonist Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy

Start date: March 30, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to : 1. Use of the aromatase inhibitor( letrozole) for the treatment of ectopic pregnancy compared to methotrexate. 2. Use of the Gnrh antagonist for the treatment of ectopic pregnancy compared to methotrexate.

NCT ID: NCT04176549 Recruiting - Ectopic Pregnancy Clinical Trials

Assessment of Biomarkers in Ectopic Pregnancy

AMBER
Start date: November 18, 2019
Phase:
Study type: Observational

To further develop a patient care pathway (incorporating a statistical model which uses the values of biomarkers) in routine clinical practice that will aid the diagnosis and management of women with an ectopic pregnancy.

NCT ID: NCT04127149 Completed - Pneumonia Clinical Trials

Evaluation of Ultra-portable Ultrasound in General Practice

EPEMedG
Start date: December 3, 2019
Phase: N/A
Study type: Interventional

This is an interventional multi-centre study comparing two groups of general practitioners with or without an ultrasound scanner over a period of 6 months. The evaluation focuses on the management of patients for 8 pathologies: - Pneumonia - Pleural effusion - Renal colic - Hepatic colic or cholecystitis - Subcutaneous abscess or cyst - Fracture of long bones - Intra-uterine pregnancy or extra-uterine pregnancy or miscarriage - Phlebitis The principal hypothesis is that there are fewer complementary exams in the group of doctors using ultrasound scanners. The secondary hypotheses are: - There is better patient orientation (emergency care, specialist consultation, return home) in the group of doctors using the ultrasound scanners. - The global cost of the care is lower in the group of doctors using the ultrasound. - Using ultrasound during the consultation decreases the anxiety of the patient. - Using ultrasound increases the duration of the consultation. - There is no difference between the predicted and the real orientation of the patients.

NCT ID: NCT04096872 Recruiting - Clinical trials for Cervical Cancer, Endometrial Cancer,Endometrial Lesion & Adnexal Lesion,Ectopic Pregnancy & Infertility,Pelvic Obstructive Disorder & Genital Tract Deformity

Clinical Application of Laparo-endoscopic Single-site Surgery and Natural Orifice Transluminal Endoscopic in Gynecology

GLESS
Start date: November 1, 2017
Phase:
Study type: Observational [Patient Registry]

The GLESS registry is a prospective multi-center observational registry. Data from the time of patient admission, operation, discharge, and follow-up will be collected for this registry. Eight gynecological conditions included were: cervical cancer, endometrial cancer, endometrial lesion, adnexal lesion, ectopic pregnancy, infertility, pelvic obstructive disorder, and genital tract deformity.

NCT ID: NCT04071574 Completed - Clinical trials for Polycystic Ovary Syndrome

Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility

CS-EOSP-ICSI
Start date: February 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

The study will describe the effectiveness of ovarian stimulation in correlation with female infertility causes in a Lebanese population: a comparative study using 5 protocols of ovulation induction (treatment with "A" gonadotropins alone, "B" short GnRH agonist, "C" multiple-dose GnRH antagonist, "D" long GnRH agonist and "E" combined protocol of GnRH antagonist and agonist) and the outcomes of ICSI. This comparative study will help clinicians to select the relevant protocol of ovarian stimulation related to the female infertility disorders.

NCT ID: NCT03974841 Completed - Ectopic Pregnancy Clinical Trials

Cornual Wedge Resection Outcome

Start date: January 1, 2016
Phase:
Study type: Observational

Cornual pregnancy is a rare form of ectopic pregnancy that accounts for 2% to 4% of ectopic pregnancies, with a mortality rate between 2.0% and 2.5%. Traditionally, interstitial pregnancies were treated by laparotomy with cornial resection or hysterectomy. However, nowadays, increasingly interstitial pregnancies are treated by laparoscopic cranial resection. Although this technique can potentially protect the fertility of the patient, it carries a serious risk of bleeding and requires a surgical experience.

NCT ID: NCT03894735 Completed - Clinical trials for Vitamin D Deficiency

Vitamin D in Ectopic Pregnancies

Start date: October 1, 2015
Phase:
Study type: Observational

According to recent evidences, vitamin D was found to have important roles in female reproductive system, both in physiological and also pathological mechanisms. Since vitamin D is tightly related with calcium metabolism, both molecules were reported to be associated with some pregnancy complications including preeclampsia, gestational diabetes, low birth weight, preterm delivery, and cesarean section rates. The aim of the present study was to evaluate the vitamin D levels in ectopic pregnancies, which may have clinical importance in the etiology of this disorder.

NCT ID: NCT03670784 Completed - Pregnancy, Ectopic Clinical Trials

Occurrence and Trend of Pregnancies Growing Outside the Womb (Ectopic Pregnancy) 2009-2018. A Study on a Defined Group of Persons

Start date: December 1, 2018
Phase:
Study type: Observational

In this trial researchers want to learn more about the occurrence of pregnancies growing outside the womb over the last decade (2009-2018) and the potential risk factors associated with pregnancies growing outside the womb. Electronic data in women who were age 15 to 44 years abstracted from health care systems such as electronic health records (EHR), regional claims systems and administrative databases were used to address research questions on ... - occurrence and trends of pregnancies growing outside the womb; - influence of method of contraception used on occurrence and trends of pregnancies growing outside the womb; - potential risk factors associated with pregnancies growing outside the womb; - trends in management of pregnancies growing outside the womb over the last decade.