Cervical Cancer, Endometrial Cancer,Endometrial Lesion & Adnexal Lesion,Ectopic Pregnancy & Infertility,Pelvic Obstructive Disorder & Genital Tract Deformity Clinical Trial
Official title:
Clinical Application of Laparo-endoscopic Single-site Surgery and Natural Orifice Transluminal Endoscopic in Gynecology- the Chinese National Registry
The GLESS registry is a prospective multi-center observational registry. Data from the time of patient admission, operation, discharge, and follow-up will be collected for this registry. Eight gynecological conditions included were: cervical cancer, endometrial cancer, endometrial lesion, adnexal lesion, ectopic pregnancy, infertility, pelvic obstructive disorder, and genital tract deformity.
Founding of the group. In June 2016 with the support of the Chinese Medical Doctor's
Association and Chinese OBGYN Association, the not-for-profit GLESS (including Notes) Working
Group was founded. The national Working Group is tasked with creating and maintaining the
Prospective GLESS data registry, standardizing LESS surgeon training, creating best practices
and guidelines. The Working Group aims to extend to all 35 provinces in Mainland China
covering over 200 hospitals nationwide.
The GLESS Working Group published an expert consensus in 2017 on the indications and
contraindications of the surgery. The GLESS registry is a prospective observational case-only
database. Literature has cases, outcomes are positive and promising, but there lacks a
systematic and large scale multi-center registry to provide data driven evidence for best
practices.
The goal for the group (evidence level- can we achieve level 1, Canada task force). Research,
share experiences to identify indications, standard surgical practices, understand
outcomes/observations. Provide empirical evidence for GLESS and Notes surgical indications
and complications. Provide empirical evidence for advancing procedures, expanding surgical
indications (e.g. can GLESS be performed on cervical cancer?), what is the reliability,
standard procedures for training Create best practices for 1)Identifying suitable clinical
indications- expanding 2)surgical techniques (entry, port placement, trochar, retraction,
suture, ligation) & selecting surgical instrumentation3)Identifying, minimizing, and handling
complications.
4)Carrying out optimal perioperative and postoperative care 5)Creating a safe and comfortable
experience in terms of cosmesis, pain, and overall experience 6)Understand how various
techniques can impact short/mid/long term for patients Outcomes will include a National
effort to coordinate followup to create the largest/most reliable data set for understanding
prognostic outcomes related to GLESS. With accumulated data/big data techniques develop
comprehensive short term and long term scoring systems for colleagues and patients around the
world. Create standard nomenclature for easier collaboration and communication between
gynecologists Note on NOTES? Why we include it here. Yes, notes is a natural progression from
LESS. With the orifice being the vagina. We believe understanding the risks/rewards of such a
procedure can make the transition from an umbilical to vaginal entry point easy.
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