The Effect of Black Currant on Postprandial Glucose Metabolism

Prediabetic State Clinical Trial

— MAQUA  

Official title:

The Effect of Black Currant on Postprandial Glucose Metabolism

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04150926
• Other study ID #: 894/2019
• Status: Completed
• Phase: N/A
• Start date: August 15, 2019
• Est. completion date: April 30, 2020

Study information

• Verified date: September 2020
• Source: University of Eastern Finland
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study examines the effect of black currant on glucose and insulin concentrations after a meal. In addition, the cytokine and free fatty acids levels are of interest.

Description:

The study examines the effect of black currant on glucose and insulin concentrations after a meal.

Healthy (n= 30) volunteers are recruited to participate in four consecutive visits in the research laboratory, when four meals are served in randomised order. Meals are: black currant puree, black currant and quinoa based snack, quinoa base and liquid containing glucose, fructose and sucrose. The meals contain the same amount of carbohydrates.

In addition to glucose and insulin concentration, cytokine and free fatty acid concentrations are measured after each meal.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 26
• Est. completion date: April 30, 2020
• Est. primary completion date: February 28, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 25 Years to 65 Years

Eligibility

Inclusion Criteria:

• age: 25-65 years

• BMI: 20-28 kg/m2

• Perceived health status: Good

Exclusion Criteria:

• fasting glucose: > 7.0 mmol/l

• LDL-cholesterol: > 3.0 mmol/l

• total cholesterol: > 6.5 mmol/l

• blood pressure : > 160/100 mmHg

• weight change of > 5% during previous 6 months or active weightreduction

• no serious chronic diseases

• one exception of the exclusion criteria maybe accepted after the MD consideration

Related Conditions & MeSH terms

• Hyperglycemia
• Postprandial Hyperglycemia
• Prediabetic State

Intervention

Other:
• Black currant
The effect of black currant puree will be compared with black currant-quinoa product, quinoa base and with liquid with glucose, fructose and sucrose Experimental: Black currant and quinoa product Active Comparator: Quinoa base Meal study comparing the effect of black currant puree with liquid with glucose, fructose and sucrose, black currant and quinoa product and quinoa base
• Black currant-quinoa product
The effect of black currant puree will be compared with black currant-quinoa product
• Quinoa base
The effect of black currant puree will be compared with quinoa base

Locations

Country	Name	City	State
Finland	University of Eastern Finland	Kuopio

Sponsors (3)

Lead Sponsor	Collaborator
University of Eastern Finland	Regional Development Company SavoGrow, Savonia University of Applied Sciences

Country where clinical trial is conducted

Finland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Glucose concentration	Glucose concentration after meal	0 minutes until 180 minutes
Primary	Insulin concentration	Insulin concentration after meal	0 minutes until 180 minutes