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NCT00932932 Clinical Trial

Cortisol Activity in Patients With Prader-Willi Syndrome and Healthy Controls

Prader-Willi Syndrome Clinical Trial

Official title:
11 Beta Hydroxysteroid Dehydrogenase 1 (11-beta HSD 1) Activity in Patients With Prader-Willi Syndrome and in Healthy Controls

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00932932
Other study ID # 09 01-014
Secondary ID
Status Completed
Phase N/A
First received July 2, 2009
Last updated June 23, 2011
Start date February 2009
Est. completion date August 2010

Study information
Verified date June 2011
Source Children's Mercy Hospital Kansas City
Contact n/a
Is FDA regulated No
Health authority United States: Institutional Review Board
Study type Observational

Clinical Trial Summary

The purpose of the study is to find out if people with Prader-Willi syndrome have a difference in the protein which changes inactive cortisone to the active stress hormone cortisol.

Recruitment information / eligibility
Status Completed
Enrollment 36
Est. completion date August 2010
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 6 Months and older
Eligibility Inclusion Criteria:

- Prader-Willi syndrome confirmed by molecular testing, ages 6 months to adult

- Controls: Age-matched, sex-matched, developmentally normal, BMI-controlled healthy or obese subjects

Exclusion Criteria:

- PWS subjects without molecular confirmation of the diagnosis

- Subjects receiving glucocorticoid treatment within 3 months of evaluation

- Subjects receiving growth hormone within one year prior to analysis

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Children's Mercy Hospital Kansas City
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