Perioperative Intravenous Lidocaine in Liver Surgery

Status Recruiting

Clinical Trial Summary

This is a randomized double blinded placebo-controlled study, conducted in Lund, Sweden. Patients will be randomized in two groups, with a ratio of 1:1. The experimental arm will receive intravenous Lidocaine perioperatively, and the Control arm will receive placebo, i.e. normal Saline. Postoperative both arms will get routine pain Control with PCA, Patient Controlled Analgesia with an intravenous Oxycodone-infusion. Outcome-measures will include patients pain intensity scoring, and opioid consumption.

Clinical Trial Description

Patientes will be randozied in blocks of eight. The experimental arm will receive a bolus of 1,5mg/kg before induction of anesthesia, immediately followed by an infusion of 1,5mg/kg/h until 1 hour post surgery. The placebo arm will receive the same amount of normal Saline instead. Pain intensity scoring, measured by Numerical Rating Scale, NRS, will be conducted at 1, 2, 4 hour postoperatively, and each morning and night until discharge, or for a maximum 5 Days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05153785
Study type	Interventional
Source	Lund University Hospital
Contact	Emil Östrand, MD
Phone	+46-(0)46-171000
Email	emil.ostrand@skane.se
Status	Recruiting
Phase	Phase 2/Phase 3
Start date	November 15, 2021
Completion date	December 31, 2026

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