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Clinical Trial Summary

A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in children in perioperative settings.


Clinical Trial Description

Children often suffer acute pain,awakening delirium, anxiety and depression after operation which may affect the recovery of children. S (+) - ketamine has been described to decrease acute pain and opioid consumption,but it needs to confirm for chinese children undergoing surgery. Objective: To evaluate the analgesic effect of perioperative administration of S (+) - ketamine on postoperative acute pain in children undergoing surgery, and explore the effects of S (+) - ketamine on postoperative awakening delirium, postoperative anxiety and depression mood ,as well find the best usage, including dose, timing, compatibility, and type of operation. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04834427
Study type Interventional
Source Chinese PLA General Hospital
Contact
Status Enrolling by invitation
Phase Phase 4
Start date April 20, 2022
Completion date December 4, 2024

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