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Postoperative Nausea clinical trials

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NCT ID: NCT06422793 Not yet recruiting - Clinical trials for Postoperative Nausea

The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery

Start date: July 31, 2024
Phase: N/A
Study type: Interventional

Postoperative nausea and vomiting (PONV) is a major concern for patients undergoing orthognathic surgery (corrective jaw surgery). These symptoms affect up to 60% of jaw surgery patients and can be quite distressing. The mechanisms underlying PONV are complex, but it is thought that surgical site bleeding and blood pooling in the stomach is the primary stimulus in this type of surgery. Nasogastric (NG) tubes have been used to suction out pooled blood in the stomach (gastric decompression), in hopes of minimizing symptoms. However, new research shows that NG tube gastric decompression may not demonstrate any benefit, and may even worsen PONV. Our study aims to directly compare PONV in participants undergoing gastric decompression or not. Participants will be randomized into two groups, either no NG tube gastric decompression or NG tube gastric decompression throughout the surgery and removed approximately one hour postoperatively. It is hypothesized that there will be less PONV in the group that does not undergo gastric decompression. We hope that the results from this study will better patient outcomes for this common postoperative problem and guide future practices for NG tube gastric decompression in orthognathic surgery.

NCT ID: NCT05632224 Not yet recruiting - Vomiting Clinical Trials

Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery

PONV
Start date: November 24, 2022
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare frequency with postoperative nausea and vomiting in ASA( American Society of Anesthesiologists) I, II patients undergoing laparoscopic surgery. The main question[s] it aims to answer are: - Primary Outcome is the incidence of nausea and vomiting between 0-6 and 6-24 hours postoperatively and the need for additional antiemetics - Secondary outcome is detection of additional analgesic needs and complications between 0-6 and 6-24 hours postoperatively. Participants will receive aprepitant or granisetron for prevention of postoperative nausea and vomiting.

NCT ID: NCT05302128 Not yet recruiting - Clinical trials for Laparoscopic Cholecystectomy

The Effect of Cold Vapor on Nausea and Vomiting in the Early Postoperative Period After Laparoscopic Cholecystectomy

Start date: April 11, 2022
Phase: N/A
Study type: Interventional

Postoperative nausea and vomiting (PONV) was defined by the American Society of PeriAnesthesia Nurses (ASPAN) as nausea and/or vomiting in the first 24 hours after surgery and is among the most common complications after pain in patients undergoing surgery. PONV is divided into three as early, late, and delayed. Nausea-vomiting developing within 2-6 hours after surgery is classified as early, nausea-vomiting developing within 6-24 hours after surgery is classified as delayed, and nausea and/or vomiting developing within the first 24 hours after surgery are classified as delayed PONV. PONV increases the length of stay in the recovery room, delays starting oral intake, causes fluid and electrolyte imbalance, and causes pain, dehydration, delayed wound healing, decreased patient comfort, prolonged hospitalization, and increased cost. Therefore, the prevention and management of nausea and vomiting in the perioperative period in surgical patients are very important.

NCT ID: NCT04432259 Not yet recruiting - Postoperative Pain Clinical Trials

Oral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee Arthroplasty

Start date: July 2020
Phase: Phase 4
Study type: Interventional

This study aims to determine if oral dexamethasone provides clinically significant improvement in postoperative outcomes, specifically nausea and pain scores.

NCT ID: NCT03639012 Not yet recruiting - Postoperative Pain Clinical Trials

Outcomes of Carbohydrate Loading Paediatric Patients Preoperatively for Tonsillectomy and Adenoidectomy

Start date: September 2018
Phase: N/A
Study type: Interventional

Randomised control trial of 150 paediatric patients aged between 3-8years. One group will receive a preoperative carbohydrate oral drink and the other group will receive current standard care (no drink) prior to undergoing tonsillectomy and/or adenoidectomy. Outcomes to be reported will be: 1) patient and parent satisfaction; 2) post operative pain score at: recover, 1 hour post op, prior to discharge home and then day 1 postoperatively; 3) PONV rates in recovery, prior to discharge home and again on Day 1 postoperatively; 4) sleep quality night after surgery.

NCT ID: NCT03271749 Not yet recruiting - Lung Cancer Clinical Trials

Protocol for Accelerated Recovery in Patients Undergoing Thoracic Surgical Procedures (PROSM). Study Randomized Comparative Between the Adoption of the Proposed Guidelines and the Traditional Method Currently Used in the Institution

PROSM
Start date: July 1, 2021
Phase: N/A
Study type: Interventional

Introduction: Aiming at reducing costs and optimizing the use of these financial resources, several postoperative recovery protocols have emerged that aim to reduce the length of hospital stay by accelerating surgical recovery.1,2 In view of the current Brazilian political and economic scenario allied to the existing scientific knowledge on the subject , the investigators developed a protocol that aims to meet this need using resources already available and offered in brazilian public health system. The investigators called this protocol as Protocol of Operative Recovery Santa Marcelina (PROSM) that had as inspiration the protocols of accelerated postoperative recovery already used in several European health services. Goals: 1. To evaluate the impact of PROSM on the length of hospitalization in days and postoperative pain (visual analog pain scale - VAS) in patients submitted to surgical procedures performed by the thoracic surgery team of the Hospital Santa Marcelina de Itaquera. 2. Evaluate the impacts of PROSM in reducing the costs (US dollars) of surgical treatment and hospitalization of these patients. Materials and methods: A group of 200 patients with elective pulmonary resections (segmentectomies, lobectomies or pneumonectomies) to treat neoplastic lung diseases will be selected by the investigators. The participants will be randomized into two groups (rate of randomization 1/1). The first group will be submitted to the standard surgical treatment that is currently used in Santa Marcelina - Itaquera hospital. The second group will be submitted to treatment with the adoption of the PROSM guidelines, which will be detailed later. Investigators will evaluate in the two groups: surgical time in minutes, intraoperative complications: intraoperative bleeding in mililiters, need for transfusion of blood products, intraoperative clinical complications. Investigators will also evaluate the need for postoperative recovery in Intensive Care Unit (ICU), medications used to maintain the anesthetic plane during the procedure (amount of drugs in milligrams), medications used for postoperative analgesia, length of hospital stay in days, postoperative clinical complications, need for surgical re-boarding, immediate postoperative pain (VAS), postoperative pain at the time of discharge and the first outpatient return (VAS), the need for opioid analgesics at home after discharge. After the data collection, the investigators will analyze them and make a comparative study of the costs of surgical treatment and hospitalization between the two groups. This data will be obtained from the billing department of the Hospital Santa Marcelina de Itaquera.

NCT ID: NCT01389570 Not yet recruiting - Clinical trials for Postoperative Nausea

Postoperative Nausea/Vomiting and Acupressure

Acunausea
Start date: September 2011
Phase: Phase 2
Study type: Interventional

Postoperative nausea and vomiting (PONV) remain a significant challenge in our practice. However, pharmaceutical prophylaxis can confer unpleasant adverse effects. It would therefore be appropriate to consider the use of non-pharmacological methods in preventing PONV. Acupuncture and acupressure are reported to be effective preventive treatment for PONV, and the adverse effects are minimal. Consequently, the aim of the study is to implement acupressure in our anaesthetic department procedures. A reduction of the use of antiemetics will be a parameter on the effectiveness of acupressure. The study will focus on acupressure as a supplement to the ordinary prophylactic treatment of PONV in adults undergoing orthopaedic and general surgery, and adults and children undergoing ear, nose, throat surgery. The primary endpoints are the quantities of antiemetics used before (baseline) and during the implementation period. The study will be conducted from January to December 2011.