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Oral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee Arthroplasty

Postoperative Pain Clinical Trial

Official title:
Oral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee Arthroplasty

Clinical Trial Summary

This study aims to determine if oral dexamethasone provides clinically significant improvement in postoperative outcomes, specifically nausea and pain scores.

Clinical Trial Description

Protocols in perioperative pain management during total joint arthroplasty (TJA) have contributed to early discharge after surgery. As practices move to favor ambulatory surgery in total joint arthroplasty changes must be made to postoperative pain and nausea management. Spinal anesthesia has been essential in managing associated ambulatory TJA, however, nausea and vomiting are known detrimental side effects. The use of systemic steroids has also been shown in the literature to reduce pain scores, length of stay, the need for antiemetics, and increase the distance of ambulation without increasing the rate of surgical site infection or prosthetic joint infection. As more same-day total joint replacement is incorporated into practice, an oral alternative may prove beneficial. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04432259
Study type Interventional
Source Henry Ford Health System
Contact Jonathan Shaw, M.D.
Phone 414-405-8544
Email jshaw5@hfhs.org
Status Not yet recruiting
Phase Phase 4
Start date July 2020
Completion date December 2022
View Details
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