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Postoperative Hemorrhage clinical trials

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NCT ID: NCT05077124 Recruiting - Clinical trials for Blood Loss, Surgical

Safe and Timely Antithrombotic Removal (STAR) Registry

Start date: September 30, 2021
Phase:
Study type: Observational

This registry will capture real-world clinical use patterns and associated clinical outcomes with the use of CytoSorb for the removal of antithrombotic agents.

NCT ID: NCT05047133 Recruiting - Clinical trials for Postoperative Blood Loss

Effect of Early Administration of TXA in Adult Hip Fractures

Start date: September 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

This is a prospective clinical study designed to assess blood loss in intracapsular and extracapsular hip fractures undergoing operative fixation at a Level II trauma center. It is well established in the orthopedic literature that tranexamic acid (TXA) decreases blood loss and need for postoperative blood transfusion in hip fracture patients as well as total joint arthroplasty patients. A typical dosing pattern, and the dosing pattern employed at our institution, is 1 gram IV infused prior to incision followed by 1 gram IV infused at the time of wound closure.

NCT ID: NCT04855877 Recruiting - Clinical trials for Anterior Cruciate Ligament Rupture

Oral Administration of Tranexamic Acid in Anterior Cruciate Ligament Surgery Reduce Postoperative Haemarthrosis

Start date: July 6, 2021
Phase: Phase 4
Study type: Interventional

To find superiority relationship between oral and intravenous administration of tranexamic acid on peroperative and postoperative blood loss, haemarthrosis prevalence and improvement functional prognosis in anterior cruciate ligament arthroscopy.

NCT ID: NCT04725305 Recruiting - Postoperative Pain Clinical Trials

BiZact Tonsillectomy in the Pediatric Population

Start date: June 6, 2021
Phase: N/A
Study type: Interventional

This study has been designed to evaluate how effective the Bizact tonsillectomy device is in reducing operating time and complications that occur after surgery. This device operates in a different way than the standard device that is used for most tonsillectomies. In 2019, a study was conducted in 186 children and adults using this device in tonsillectomies. Results showed lower blood loss and shortened time in surgery. However, the rate for bleeding as a complication after surgery was the same as other procedures that are used in tonsillectomy

NCT ID: NCT04672213 Recruiting - Clinical trials for Postoperative Blood Loss Following Spine Surgery

TXA in Spine Surgery

Start date: December 15, 2017
Phase: N/A
Study type: Interventional

As tranexamic acid (TXA) becomes more prevalent, all patients are receiving the same dose and method of delivery regardless of their pre-operative risk of transfusion. Therefore, the aim of the study is to determine whether or not repeated dosing of oral or a different method of delivery like intravenous (IV) TXA reduces the post-operative reduction in hemoglobin, hematocrit, number of transfusions, and postoperative blood loss following open spine surgery.

NCT ID: NCT04613635 Recruiting - Morbid Obesity Clinical Trials

Stratafix vs. Vicryl OAGB / MGB Suture Study

Start date: November 6, 2020
Phase: N/A
Study type: Interventional

To compare shorttime (6 months) results of two competitive suture materials with regard to time demanded to perform the concerned surgical step and secondary to study anastomotic site safety and complications like leakage and hemorrhage as well as development of anastomotic strictures. Evaluation of cost-effectiveness.

NCT ID: NCT03204357 Recruiting - Cardiac Disease Clinical Trials

Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass

Start date: January 24, 2022
Phase: N/A
Study type: Interventional

Autologous blood transfused at the end of cardiopulmonary bypass will reduce total blood loss 24 hours after surgery and improve mitochondrial oxygen delivery measured by plasma succinate levels. The study design is a prospective randomized interventional trial of transfusion of fresh autologous whole blood versus standard of care expectant management of bleeding during elective cardiac surgery.

NCT ID: NCT03124030 Recruiting - Dental Diseases Clinical Trials

Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy

NOADB
Start date: August 2, 2016
Phase: N/A
Study type: Observational

Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral anticoagulants. The aim of the present study is to observe the possible difference in intra-operative and post-operative bleeding events for single dental extraction.

NCT ID: NCT03124004 Recruiting - Clinical trials for Periodontal Diseases

Evaluation of the Intra- and Post- Operative Bleeding After Periodontal Debridement in Direct Anticoagulant Patients

NOADB_db
Start date: August 15, 2016
Phase: N/A
Study type: Observational

Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral anticoagulants. The aim of the present study is to observe the possible difference in intra-operative and post-operative bleeding events for periodontal debridement.

NCT ID: NCT03070665 Recruiting - Clinical trials for Gastrointestinal Disease

Blood Pressure During ESD is Related With the Postoperative Bleeding

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Endoscopic submucosal dissection(ESD) is a prominent minimally invasive operation technique for treating early gastrointestinal tumor. But promoting ESD is uneasy because of its complications such as postoperative bleeding, perforation and so on. So if we decrease the rate of postoperative bleeding, ESD might be better popularized. Some study indicated that hypertension was the independent risk factor of postoperative bleeding. Endoscopic center of Fudan University Zhongshan Hospital is a rich experienced medical unit in doing ESD operation in China. Referring to our experience, if we can use some special methods to find the potential bleeding spot which is not obvious during ESD operation and we coagulate it precisely, then we may control the risk of postoperative bleeding. Based on the above hypothesis, our team designed this study to examine whether increasing blood pressure during gastric ESD could help to control the risk of postoperative bleeding.