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Postoperative Complications clinical trials

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NCT ID: NCT05721391 Completed - Clinical trials for Postoperative Complications

Impact of Frailty on Postoperative Complications in Oncosurgery

Frailty
Start date: March 1, 2022
Phase:
Study type: Observational

Advanced ageing is accompanied by loss of reserve in multiple organ systems leading to increased risk of complications after surgery.Frailty is a functional syndrome involving reduced physiological reserve and 25-56% of all elderly surgical patients are reported to be frail .

NCT ID: NCT05721144 Completed - COVID-19 Clinical Trials

Inhaled NO in Surgical Patients With Recent COVID-19 Infection

INORDINATE
Start date: February 17, 2023
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the effect of perioperative inhalation of NO on reducing the incidence of postoperative pulmonary complications in patients with recent COVID-19 infection, and to evaluate whether inhaled NO can improve the prognosis of patients. The investigators will enroll 660 surgical patients who was infected with SARS-CoV-2 within 42days (7 weeks ) prior to planed surgery under general anesthesia. Patients will be randomized to receive either inhaled nitric oxide (per protocol) or a placebo. Perioperative standards of care will be the institution's own protocols (such as ventilation strategies and use and dose of anesthetics, analgesia and fluid management, etc).

NCT ID: NCT05711355 Completed - Clinical trials for Meningomyelocele/Spina Bifida

the Effects of Platelet-Rich Plasma on Postoperative Complications After Meningomyelocele

Start date: January 15, 2022
Phase: N/A
Study type: Interventional

Introduction: Meningomyelocele is a common congenital neural tube defect. To reduce complications, early surgery and a multidisciplinary approach is needed. In this study, the investigators administered platelet-rich plasma (PRP) to newborns with meningomyelocele following corrective surgery to minimize cerebrospinal fluid (CSF) leakage and accelerate the healing of the immature pouch tissue. The investigators compared these with a control group that did not receive PRP. Patients and Methods: Of the 40 newborns who were operated on with the diagnosis of meningomyelocele, 20 patients received PRP after surgical repair, and 20 were followed up without PRP. In the PRP group, 10 of the 20 patients underwent primary defect repair, the other 10 underwent flap repair. In the group that did not receive PRP, primary closure was performed in 14 patients and flap closure in six.

NCT ID: NCT05706688 Completed - Clinical trials for Perioperative/Postoperative Complications

Effect of Regional Versus General Anesthesia on Thirty-day Outcomes Following Carotid Endarterectomy: a Matched-pairs Cohort Study.

Start date: January 1, 2015
Phase:
Study type: Observational

The goal of this observational study is to assess the effect of regional versus general anesthesia on carotid endarterectomy thirty-day outcomes. The main questions it aims to answer are: - Is regional anesthesia associated with lower incidence of major morbidity and mortality? - Is regional anesthesia associated with lower incidences of secondary adverse events? Participants will be sampled from the 2015-2019 American College of Surgeons National Surgical Quality Improvement Program

NCT ID: NCT05689840 Completed - COVID-19 Clinical Trials

Association Between Post-covid Infection Status and Perioperative Morbidity: A Ambispective Cohort Study

Start date: December 1, 2022
Phase:
Study type: Observational [Patient Registry]

With the knowledge of currently transmitted omicron variant being less virulent, over 90 percent of the Chinese population is fully vaccinated, and the Chinese health workers have sufficient experience treating the illness. China 's epidemic prevention and control has entered a new stage to restore the normal functioning of society and basic medical services, On Dec, 7, China released a circular on further optimizing its COVID-19 response, announcing 10 new prevention and control measures.This has marked the watershed for sharply increased number of elective surgical patients diagnosed with COVID-19 during preoperativley, fully recovered or during recovery. Beijing faced a wave of omicron infection starting that would result in of a wide range of population infections. At which time there is limited evidence regarding the optimal timing of surgery following SARS-CoV-2 infection especially for omiron among Chinsese patients .This study intends to explore the relationship between the incidence of postoperative complications after elective surgery and COVID-19 infection in Peking Union Medical College Hospital, and provide data support for the policy formulation of elective surgical timing for patients after COVID-19 infection.

NCT ID: NCT05680623 Completed - Clinical trials for Postoperative Complications

Clinical and Economic Validation of the ISGPS Definition of PPAP

ISGPS-PPAP
Start date: January 1, 2022
Phase:
Study type: Observational

This prospective validation study aims to investigate the incidence of PPAP after pancreaticoduodenectomy (PD) by applying the ISGPS definition and grading system, to demonstrate its clinical impact by examining associated postoperative outcomes, and to validate its applicability through an economic assessment.

NCT ID: NCT05679973 Completed - Clinical trials for Impacted Third Molar Tooth

Evaluation of the Efficacy of Polybutester Suture on Postoperative Complications in Lower Impacted Third Molar Surgery

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This study aimed to evaluate the efficacy of polybutester sutures on postoperative complications in lower impacted third molar surgery.

NCT ID: NCT05672238 Completed - Acute Kidney Injury Clinical Trials

Evaluation of Postoperative Acute Kidney Injury (AKI) Incidence and Risk Factors in Patients Underwent Pneumonectomy

Start date: October 16, 2021
Phase:
Study type: Observational

Acute kidney injury (AKI) is a critical complication associated with a high incidence of morbidity and mortality that can occur in critically ill patients and after major surgical procedures. The aim of this study is to identify the incidance and outcomes of patients underwent pneumonectomy, defined by Kidney Disease Improving Global Outcomes (KDIGO) criteria.

NCT ID: NCT05647486 Completed - Clinical trials for Postoperative Complications

Predictors of 30-day Postoperative Outcome After Elective EVAR

Start date: March 23, 2016
Phase:
Study type: Observational

This study investigated the 30-day postoperative outcome after elective EVAR and the role of possible predictors among patients' baseline characteristics

NCT ID: NCT05642988 Completed - Surgery Clinical Trials

Application of Wearable Technology in High-risk Surgical Patients in the Perioperative Period

Start date: March 1, 2023
Phase:
Study type: Observational

Unrecognised changes in patients' vital signs after surgery can result in preventable complications. Current standard practice includes routine monitoring of patient vital signs up until hospital discharge. Upon discharge from hospital, all forms of routine vital sign monitoring ceases. The availability and use of wearable technology in healthcare is increasing rapidly. The role of wearable technology in the remote monitoring of patients at high-risk of post-operative complications and hospital readmission after discharge from hospital is unclear. This pilot study is aimed to assess the feasibility of using wearable technology in patients recovering from major intracavity surgery after hospital discharge in the Irish healthcare setting.