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Postoperative Complications clinical trials

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NCT ID: NCT04663958 Completed - Cancer Clinical Trials

Predictive Value of Ariscat Index In The Development of Pulmonary Complication After Major Abdominal Cancer Surgery

Start date: December 21, 2020
Phase:
Study type: Observational

The term postoperative pulmonary complication is the development of any complications affecting the respiratory system after anesthetic and surgery procedures. The ARISCAT risk assessment score is a seven-variable regression model that divides patients into low, moderate, and high-risk groups. In this study, the investigators aimed to investigate the effectiveness of the ARISCAT risk scoring index in predicting postoperative pulmonary complication development in patients scheduled for major abdominal cancer surgery.

NCT ID: NCT04662515 Completed - Clinical trials for Postoperative Complications

NOACs in Oral and Maxillofacial Surgery: Impact on Post-operative Complications

Start date: June 1, 2016
Phase:
Study type: Observational

Aims: To investigate the incidence of bleeding complications during oral surgical procedures in patients medicated with DOACs. To investigate the perioperative and postoperative bleeding volume during oral surgical procedures in patients medicated with DOACs. To examine whether increased perioperative bleeding volume complicates the planned intervention, thereby prolonging the operation time. Previous studies have shown that the incidence of healthcare-consuming bleeding complications following oral surgical procedures in patients who are prescribed warfarin is approximately 4% (9). To investigate whether the incidence is higher or lower by the intake of DOAC it is considered to be sufficient with 100 patients in each group. The groups consist of patients who are prescribed warfarin, DOACs, as well as a control group. Hypothetical outcomes: The incidence of bleeding complications and the perioperative and postoperative bleeding volume during oral surgical procedures in patients medicated with DOACs are higher compared to patients medicated with warfarin and patients taking no anticoagulants. Increased perioperative bleeding volume complicates the planned intervention, thereby prolonging the operation time. Clinical relevance: The study will serve as a basis for the development of treatment guidelines for patients who medicate with DOACs. If it turns out that the oral surgery procedure presents no increased risk of complications and that the bleeding volume does not complicate the surgery significantly, it may be recommended that patients who medicate with DOACs whom are in need of oral surgical procedures seek ordinary dental care.

NCT ID: NCT04655885 Recruiting - Clinical trials for Primary or Metastatic Hepatic Adenocarcinoma

Cardiac Output Optimization on Postoperative Complications in Major Hepatic Surgery

OPTILIVER
Start date: February 3, 2022
Phase: N/A
Study type: Interventional

Major hepatectomies are high-risk surgeries offered more and more frequently for the curative treatment of primary or secondary liver cancer, and for complex cases, representing a real challenge for medical teams. The 1st peroperative phase of "hepatic resection" requires a minimum supply of filling fluids to limit perioperative bleeding (Low Central Venous Pressure). However this strategy exposes the risk of organ hypoperfusion due to low cardiac flow, secondary to hypovolaemia, which may lead to ischemic situations favoring the onset of postoperative complications. On the other hand, the hemodynamic management of the 2nd peroperative phase "post hepatic resection" is marked by the need to correct this hypoperfusion by optimizing cardiac output by suitable vascular filling. The major challenge is thus to restore cardiac output by refilling without excess, by correcting the hypovolemia that arose during the "post resection of the hepatic parenchyma" phase. Our hypothesis is that an individualized protocol for optimizing intraoperative cardiac flow by guided vascular filling during the "post hepatic resection" phase is accompanied by a reduction in postoperative complications in patients operated on for major hepatic surgery.

NCT ID: NCT04654299 Completed - Clinical trials for Postoperative Complications

Biliary Externalization After Pancreaticoduodenectomy

Start date: January 1, 2014
Phase:
Study type: Observational

Postoperative pancreatic fistula(POPF) is the most common complication of pancreaticoduodenectomy (PD). Sometimes POPF is associated with biliary fistula(BF), or "mixed" fistula. The purpose of this study is to assess whether the severity of the fistulae, when present, is decreased with an external biliary stent in place.

NCT ID: NCT04652180 Recruiting - Esophageal Cancer Clinical Trials

Robot-assisted Thoracic Approach Versus Open Transthoracic Esophagectomy .

CIR·ROB
Start date: November 6, 2020
Phase: N/A
Study type: Interventional

This is a randomized controlled trial designed to compare robot-assisted thoracic approach with open transthoracic esophagectomy (Ivor Lewis technique) as a surgical treatment for resectable esophageal cancer. If our hypothesis is proved correct, robot-assisted thoracic approach will result in a lower percentage of respiratory and overall postoperative complications, lower blood loss, shorter hospital stay, but with at least similar oncologic outcomes and better postoperative quality of life compared with the open transthoracic esophagectomy (current standard).

NCT ID: NCT04647968 Recruiting - Tracheostomy Clinical Trials

Primary vs Secondary Closure of Tracheo-cutaneous Fistulas

TRACH
Start date: January 12, 2021
Phase: N/A
Study type: Interventional

The mean of this study is to compare primary and secondary closure of tracheo-cutaneous fistulas and evaluate the differences in outcomes between both techniques.

NCT ID: NCT04640415 Completed - Clinical trials for Complication,Postoperative

Continuous Wireless Monitoring of Vital Signs and Automated Alerts of Postsurgical Patient Deterioration.

WARD-RCT-SX
Start date: January 11, 2021
Phase: N/A
Study type: Interventional

The primary aim of the current study is to assess the effect of continuous wireless vital sign monitoring with generation of real-time alerts, compared to blinded monitoring without alerts on the cumulative duration of any severely deviating vital signs in patients admitted to general hospital wards after major surgery. We hypothesize that continuous vital signs monitoring, and real-time alerts will reduce the cumulative duration of severely deviating vital signs.

NCT ID: NCT04630886 Enrolling by invitation - Skin Neoplasms Clinical Trials

Use of Tranexamic Acid in Reduction of Post-Op Complications in Mohs Micrographic Surgery

Start date: June 16, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to evaluate the use of locally injected tranexamic acid (TXA) under the skin during Mohs micrographic surgery for removal of skin cancers in patients on anticoagulation. TXA may be helpful in reducing bleeding and pain during surgery, and may also lead to fewer post-operative complications following surgery such as graft loss, specifically in patients on blood-thinners.

NCT ID: NCT04620850 Completed - Cesarean Section Clinical Trials

Effect of Acupressure on Recovery of Bowel Function in Patients Post Cesarean Section

Start date: November 15, 2020
Phase: N/A
Study type: Interventional

Research objectives To compare the efficacy of acupressure with no acupressure to examine time to first flatus in patient post cesarean section ; Acupressure at ST-36 Zusanli (lateral to anterior crest of tibia, in the tibialis anterior muscle) Research hypothesis Patients who received acupressure will have earlier flatus passage

NCT ID: NCT04613726 Completed - Clinical trials for Postoperative Complications

The Effect of Intravenous Granisetron and Ondansetron in Patients Undergoing Cesarean Section

Start date: December 3, 2018
Phase: Phase 3
Study type: Interventional

This study compared the effects of prophylactic intravenous (IV) infusion of ondansetron and granisetron before the spinal anesthesia on hemodynamic parameters in patients undergoing elective cesarean section.