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Postherpetic Neuralgia clinical trials

View clinical trials related to Postherpetic Neuralgia.

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NCT ID: NCT05357677 Completed - Clinical trials for Postherpetic Neuralgia

To Evaluate the Efficacy and Safety of SR419 in Patients With Postherpetic Neuralgia (PHN)

Start date: May 13, 2022
Phase: Phase 2
Study type: Interventional

This is a Phase II, international multicenter, double-blind, placebo-controlled, crossover study to assess the efficacy of SR419 in PHN subjects.

NCT ID: NCT05208918 Completed - Chronic Pain Clinical Trials

Combined Application of Pulsed RF and Steroids to the DRG for PHN

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

Recently, the use of pulsed radiofrequency has increased in many chronic pain conditions, including trigeminal neuralgia, chronic spinal pain, musculoskeletal pain, and it was recently used effectively for postherpetic neuralgia. Transforaminal epidural steroid injection has been proven in previous studies to provide effective analgesia for cases of herpes zoster-related pain. We hypothesize that the combined use of pulsed RF and steroid injection applied to the DRG may achieve better outcomes than the use of epidural steroid injection alone.

NCT ID: NCT05140863 Completed - Clinical trials for Postherpetic Neuralgia

To Evaluate the Efficacy and Safety of HSK16149 Capsule in Chinese Patients With Postherpetic Neuralgia

Start date: November 1, 2021
Phase: Phase 3
Study type: Interventional

Investigate the Efficacy and Safety of HSK16149 capsules in Chinese Postherpetic Neuralgia Following 12 Weeks Treatment in Comparison to Placebo

NCT ID: NCT04876989 Completed - Neuropathic Pain Clinical Trials

The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block

Start date: July 21, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.

NCT ID: NCT04774458 Completed - Herpes Zoster Clinical Trials

Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View

Start date: March 4, 2021
Phase: N/A
Study type: Interventional

The aim of the present study is to investigate the safety and clinical utility of contralateral oblique view for fluoroscopic guided cervical epidural access.

NCT ID: NCT04662281 Completed - Clinical trials for Postherpetic Neuralgia

Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia

RELIEF-PHN1
Start date: December 29, 2020
Phase: Phase 2
Study type: Interventional

Evaluation of the efficacy of LX9211 compared to placebo in reducing pain related to postherpetic neuralgia over an 11 week assessment period.

NCT ID: NCT04594226 Completed - Clinical trials for Postherpetic Neuralgia

Electroacupuncture Therapy for Treating Postherpetic Neuralgia

Start date: November 11, 2020
Phase: N/A
Study type: Interventional

Postherpetic neuralgia (PHN) has a high incidence rate and severely impact on quality of life and health care costs, interfering with physical, emotional and social functioning of affected patients. Current therapeutic options for PHN mainly include analgetic and local anaesthesia for selective nerve blockade. Nevertheless, the efficacy of analgetic is always limited by inevitable side effects, in which patients have poor compliance. Moreover, for some most suffering patients, the control of pain is often unsatisfactory despite the administration of complex combinations. As a non-pharmarceutical therapy, acupuncture is widely use for a wide range of pain conditions. Thus, it might be an alternative treatment for PHN. The aim of this multicenter randomized controlled trial is to investigate the efficacy and safety of electroacupuncture therapy in patients with postherpetic neuralgia.

NCT ID: NCT04546334 Completed - Clinical trials for Postherpetic Neuralgia

Erector Spinae Plane Block in Post-herpetic Neuralgia

Start date: September 26, 2020
Phase: N/A
Study type: Interventional

This randomized clinical study will be carried out on 72 patients admitted to the pain clinic in Tanta University Hospitals with post-herpetic neuralgia. Cases presenting to the Pain Clinic with acute pain due to postherpetic neuralgia in thoracic and/or lumbar dermatomes with numerical rating scale (NRS) of 6 or more and they will be randomly divided, using the closed envelop method, into three equal groups. Group A (24 patients): Patients will be subjected to the routine medical treatment of post herpetic neuralgia as controls (Pregabalin, acyclovir, and paracetamol) and sham erector spinae plane block Group B (24 patients): Patients will be subjected to erector spinae block by bupivacaine (2 - 2.5 mg/kg, with a maximum of 175 mg/dose) together with medical treatment. Group C (24 patients): Patients that will subjected to erector spinae block by bupivacaine (2 - 2.5 mg/kg, with a maximum of 175 mg/dose with the addition of MgSO4 (equivalent to 100 mg)) together with medical treatment. Primary outcome will be the efficacy of pain relief Secondary outcome will be the frequency of pain and the consumption of analgesics.

NCT ID: NCT04313335 Completed - Clinical trials for Postherpetic Neuralgia

Duloxetine for PHN

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

In this study, the investigators aim to investigate the preventive efficacy of prophylactic oral duloxetine during acute herpes zoster on postherpetic neuralgia and its safety.

NCT ID: NCT04099706 Completed - Chronic Pain Clinical Trials

Treatment of Chronic Postherpetic Pain With Autologous Fat Grafting - A RCT

Start date: September 19, 2019
Phase: N/A
Study type: Interventional

This randomized clinical trial investigates the possible beneficial effect of autologous fat grafting on postherpetic neuralgia.