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Posterior Capsule Opacification clinical trials

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NCT ID: NCT01734343 Completed - Cataract Clinical Trials

Posterior Capsule Opacification Development With Two Different Intraocular Lenses

MIPHY
Start date: January 2009
Phase: N/A
Study type: Interventional

Age-related cataract is the main cause of impaired vision in the elderly population worldwide. The only treatment that can restore functional visual ability is cataract surgery where the opacified crystalline lens is removed by phacoemulsification and an artificial intraocular lens is implanted into the remaining capsular bag. Cataract operations are generally very successful, with a low risk of serious complications. The most common reason for impaired vision after uneventful cataract surgery in otherwise healthy eyes is the development of posterior capsule opacification (PCO). PCO is a physiological change (thickening, opacification and clouding) of the capsular bag expected after cataract surgery, because the lens epithelial cells (LECs) undergo hyperplasia and cellular migration. PCO is treated with Nd:YAG capsulotomy, a quick outpatient procedure that uses a laser to open a central hole in the posterior capsular bag. Modifications in IOL design and material lead to a decrease in the incidence of PCO. During the past two decades, refinements in surgical technique were made resulting in today's small incision phacoemulsification surgery. Nowadays a multitude of microincision IOLs are available, many of them similar but of course with some differences in regard to the chemical composition of the acrylic material and the IOL design. The purpose of this study is to compare the development of posterior capsule opacification (PCO) and the frequency of treatment between two different microincision IOLs over a period of 3 years.

NCT ID: NCT01125345 Completed - Clinical trials for Posterior Capsule Opacification

Posterior Capsule Opacification (PCO) With Single Piece Hydrophobic Versus Hydrophillic Intraocular Lens (IOL)

Start date: January 2006
Phase: Phase 4
Study type: Interventional

The purpose of the study was to compare the postoperative PCO results of the single-piece hydrophobic Acrylic IOLs versus the newer generation single-piece hydrophilic Acrylic IOLs in patients undergoing bilateral cataract surgery.

NCT ID: NCT00855491 Completed - Clinical trials for Posterior Capsule Opacification

Posterior Capsule Opacification (PCO) With AcrySof Single-Piece IOL

Start date: July 2003
Phase: N/A
Study type: Interventional

The purpose of this study what to evaluate if axial myopia might influence the development of PCO.