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Clinical Trial Summary

The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by FDA and on the market for post-surgical pain control. The investigators plan on randomizing study participants to either Exparel or Zynrelef at the closure site of robotic sleeve gastrectomy and assessing their pain control postoperatively both in the hospital and at home. The investigators will measure the outcome of two drugs, Zynrelief, and Exparel on postoperative pain score -using the NRS pin score up to 72 hours after surgery. The total opioid use will be recorded in forms that will be used to measure pain score and total opioid use and will be collected to the Excel sheet. The cost of the drug will be calculated for internal use for Hospital purpose only.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06349772
Study type Interventional
Source Texas Tech University Health Sciences Center
Contact Tommy Wright, DO
Phone 8176888021
Email tommy.wright@ttuhsc.edu
Status Not yet recruiting
Phase Early Phase 1
Start date November 1, 2024
Completion date April 1, 2025

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